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帕金森病和非典型帕金森综合征的神经影像学

Neuroimaging of Parkinson's disease and atypical parkinsonism.

作者信息

Zgaljardic Dennis J, Feigin Andrew

机构信息

Center for Neurosciences, North Shore-Long Island Jewish Research Institute, 350 Community Drive, Manhasset, NY 11030, USA.

出版信息

Curr Neurol Neurosci Rep. 2004 Jul;4(4):284-9. doi: 10.1007/s11910-004-0053-1.

DOI:10.1007/s11910-004-0053-1
PMID:15217542
Abstract

The basal ganglia and its associated circuitry can be assessed with a variety of neuroimaging methods that can provide information regarding specific neurotransmitter systems, the functional activity of brain regions, and the structural integrity of these regions. In Parkinson's disease (PD) and related atypical parkinsonian syndromes (APS), these imaging methods may be useful for many reasons, including aiding in differential diagnosis and measuring the efficacy of new therapies. This paper reviews recent developments in the application of neuroimaging to the assessment of PD and related APS.

摘要

基底神经节及其相关神经回路可以通过多种神经影像学方法进行评估,这些方法能够提供有关特定神经递质系统、脑区功能活动以及这些区域结构完整性的信息。在帕金森病(PD)和相关的非典型帕金森综合征(APS)中,这些成像方法可能因多种原因而有用,包括辅助鉴别诊断和衡量新疗法的疗效。本文综述了神经影像学在PD和相关APS评估应用中的最新进展。

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Neuroimaging of Parkinson's disease and atypical parkinsonism.帕金森病和非典型帕金森综合征的神经影像学
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引用本文的文献

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Frontotemporal Lobe Degeneration as Origin of Scans Without Evidence of Dopaminergic Deficit.额颞叶变性作为无多巴胺能缺乏证据的扫描结果的起源
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2
Distinguishing Parkinson's disease from atypical parkinsonian syndromes using PET data and a computer system based on support vector machines and Bayesian networks.利用正电子发射断层扫描(PET)数据以及基于支持向量机和贝叶斯网络的计算机系统区分帕金森病与非典型帕金森综合征。
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Diagnoses behind patients with hard-to-classify tremor and normal DaT-SPECT: a clinical follow up study.

本文引用的文献

1
Early stage Parkinson's disease patients and normal volunteers: comparative mechanisms of sequence learning.早期帕金森病患者与正常志愿者:序列学习的比较机制
Hum Brain Mapp. 2003 Dec;20(4):246-58. doi: 10.1002/hbm.10142.
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A review of the cognitive and behavioral sequelae of Parkinson's disease: relationship to frontostriatal circuitry.帕金森病的认知和行为后遗症综述:与额叶纹状体回路的关系。
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难以分类的震颤患者和 DaT-SPECT 正常患者的诊断背后:一项临床随访研究。
Front Aging Neurosci. 2014 Apr 1;6:56. doi: 10.3389/fnagi.2014.00056. eCollection 2014.
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使用β-CIT单光子发射计算机断层扫描(SPECT)测量帕金森病5年期间的进展速率。
Mov Disord. 2003 Nov;18(11):1266-72. doi: 10.1002/mds.10531.
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123I-Ioflupane/SPECT binding to striatal dopamine transporter (DAT) uptake in patients with Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy.123I-碘氟潘/SPECT与帕金森病、多系统萎缩和进行性核上性麻痹患者纹状体多巴胺转运体(DAT)摄取的结合情况
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6
[A follow-up study on brainstem atrophy in progressive supranuclear palsy--when does brain MRI contribute to the differential diagnosis between progressive supranuclear palsy and Parkinson disease?].[进行性核上性麻痹脑干萎缩的随访研究——脑部磁共振成像何时有助于进行性核上性麻痹与帕金森病的鉴别诊断?]
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7
The harsh realities facing the use of SPECT imaging in monitoring disease progression in Parkinson's disease.在帕金森病中使用单光子发射计算机断层扫描(SPECT)成像监测疾病进展所面临的严峻现实。
J Neurol Neurosurg Psychiatry. 2003 Oct;74(10):1447; author reply 1447. doi: 10.1136/jnnp.74.10.1447.
8
Is FDG-PET a useful tool in clinical practice for diagnosing corticobasal ganglionic degeneration?氟代脱氧葡萄糖正电子发射断层扫描(FDG-PET)在临床实践中是诊断皮质基底节变性的有用工具吗?
Mov Disord. 2003 Oct;18(10):1175-8. doi: 10.1002/mds.10498.
9
How valid is dopamine transporter imaging as a surrogate marker in research trials in Parkinson's disease?在帕金森病研究试验中,多巴胺转运体成像作为替代标志物的有效性如何?
Mov Disord. 2003 Oct;18 Suppl 7:S63-70. doi: 10.1002/mds.10581.
10
Corticobasal degeneration: structural and functional MRI and single-photon emission computed tomography.皮质基底节变性:结构与功能磁共振成像及单光子发射计算机断层扫描
Neuroradiology. 2003 Oct;45(10):708-12. doi: 10.1007/s00234-003-1058-1. Epub 2003 Sep 6.