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复杂干预措施：随机对照试验能有多“失控”？

Complex interventions: how "out of control" can a randomised controlled trial be?

作者信息

Hawe Penelope, Shiell Alan, Riley Therese

机构信息

Department of Community Health Sciences, University of Calgary, 3330 Hospital Drive NW, Calgary T2N 4N1, Alberta, Canada.

出版信息

BMJ. 2004 Jun 26;328(7455):1561-3. doi: 10.1136/bmj.328.7455.1561.

DOI:10.1136/bmj.328.7455.1561
PMID:15217878
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC437159/
Abstract

Complex interventions are more than the sum of their parts, and interventions need to be better theorised to reflect this

摘要

复杂干预并非其各部分的简单相加，干预措施需要进行更完善的理论化以反映这一点。

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Prev Sci. 2004 Mar;5(1):41-5. doi: 10.1023/b:prev.0000013980.12412.cd.
2
PRISM (Program of Resources, Information and Support for Mothers) Protocol for a community-randomised trial [ISRCTN03464021].PRISM（母亲资源、信息与支持项目）社区随机试验方案[国际标准随机对照试验编号：ISRCTN03464021]
BMC Public Health. 2003 Nov 20;3:36. doi: 10.1186/1471-2458-3-36.
3
Methodologic advances and ongoing challenges in designing community-based health promotion programs.设计基于社区的健康促进项目中的方法学进展与持续挑战。
Annu Rev Public Health. 2003;24:315-40. doi: 10.1146/annurev.publhealth.24.100901.140819. Epub 2001 Nov 6.
4
Study control, violators, inclusion criteria and defining explanatory and pragmatic trials.研究对照、违规者、纳入标准以及解释性试验和实用性试验的定义。
Stat Med. 2002 May 30;21(10):1365-76. doi: 10.1002/sim.1120.
5
Community interventions for reducing smoking among adults.减少成年人吸烟的社区干预措施。
Cochrane Database Syst Rev. 2002;2002(3):CD001745. doi: 10.1002/14651858.CD001745.
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Collective approaches for the control of depression in England.英格兰抑郁症控制的集体方法。
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A community education monitoring system: methods from the Stanford Five-City Project, the Minnesota Heart Health Program and the Pawtucket Heart Health Program.一个社区教育监测系统：来自斯坦福五城市项目、明尼苏达心脏健康项目和波塔基特心脏健康项目的方法。
Health Educ Res. 1993 Mar;8(1):81-95. doi: 10.1093/her/8.1.81.
8
Evaluating health promotion: a tale of three errors.评估健康促进：三个错误的故事。
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The tribulations of trials--intervention in communities.试验的磨难——社区干预
Am J Public Health. 1995 Feb;85(2):156-8. doi: 10.2105/ajph.85.2.156.