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[Genetic analysis of some behavioral and physiologic characters in hybrids between hypertensive and normotensive rats. Analysis of the nature of the inheritance].

作者信息

Bachmanov A A, Dmitriev Iu S

出版信息

Genetika. 1992 Jun;28(6):150-9.

PMID:1521795
Abstract

As a result of crosses between the SHR rats (spontaneously hypertensive strain) and WKY rats (normotensive strain), the F1 and F2 hybrids and the B1 and B2 backcrosses were obtained. Analysis of genetic control nature in these generations revealed that the WKY genes responsible for the level of arterial pressure, sensitivity to the electric current stimulation and salt (sodium and potassium) appetite characteristics were dominant. The heterosis effect was found for the body mass. Analysis of dynamics of different types of exploratory activity (in a shuttle box, in "horizontal plane", in an open field) demonstrated specificity of their genetic formulae and peculiarities of changes in their genetic control during the test.

摘要

相似文献

1
[Genetic analysis of some behavioral and physiologic characters in hybrids between hypertensive and normotensive rats. Analysis of the nature of the inheritance].
Genetika. 1992 Jun;28(6):150-9.
2
[The characteristics of the F1 hybrids of spontaneously hypertensive and normotensive rats].
Fiziol Zh SSSR Im I M Sechenova. 1989 Dec;75(12):1714-7.
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[Genetic analysis of various behavioral and physiologic characteristics in hybrids between hypertensive and normotensive rats. Analysis of reciprocal differences].
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[Spontaneous and orienting-exploratory motor activity in rats with hereditary arterial hypertension].[遗传性动脉高血压大鼠的自发和定向探索性运动活动]
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Preweanling behavioral development in spontaneously hypertensive, borderline hypertensive, and Wistar-Kyoto normotensive rats.自发性高血压大鼠、临界高血压大鼠和Wistar-Kyoto正常血压大鼠断奶前的行为发育
Dev Psychobiol. 1987 Jan;20(1):57-69. doi: 10.1002/dev.420200109.
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Influence of neonatal handling on blood pressure, locomotor activity, and preweanling heart rate in spontaneously hypertensive and Wistar Kyoto rats.新生期处理对自发性高血压大鼠和Wistar Kyoto大鼠血压、运动活动及断奶前心率的影响。
Dev Psychobiol. 1984 Nov;17(6):587-600. doi: 10.1002/dev.420170603.

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