Bachmanov A A, Dmitriev Iu S
Genetika. 1992 Jun;28(6):150-9.
As a result of crosses between the SHR rats (spontaneously hypertensive strain) and WKY rats (normotensive strain), the F1 and F2 hybrids and the B1 and B2 backcrosses were obtained. Analysis of genetic control nature in these generations revealed that the WKY genes responsible for the level of arterial pressure, sensitivity to the electric current stimulation and salt (sodium and potassium) appetite characteristics were dominant. The heterosis effect was found for the body mass. Analysis of dynamics of different types of exploratory activity (in a shuttle box, in "horizontal plane", in an open field) demonstrated specificity of their genetic formulae and peculiarities of changes in their genetic control during the test.