Niemann B, Rochlitz C, Herrmann R, Pless M
Department of Medical Oncology, Kantonsspital Basel, Basel, Switzerland.
Oncology. 2004;66(4):331-5. doi: 10.1159/000078335.
Toxic encephalopathy is a rarely described side effect of 5-fluorouracil which usually presents with cerebellar, neuropsychiatric, and focal neurological symptoms. Magnetic resonance imaging findings are described as patchy white matter alterations. We report the 1st case of capecitabine-induced toxic encephalopathy with epilepsy-like symptoms and diffuse white matter alterations on magnetic resonance imaging.
