Videnovic A, Semenov I, Chua-Adajar R, Baddi L, Blumenthal D T, Beck A C, Simuni T, Futterer S, Gradishar W, Tellez C, Raizer J J
Davee Department of Neurology and Neurological Sciences, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.
Neurology. 2005 Dec 13;65(11):1792-4; discussion 1685. doi: 10.1212/01.wnl.0000187313.83515.7e. Epub 2005 Oct 19.
Capecitabine is used to treat advanced breast and gastrointestinal malignancies. A single case of encephalopathy and three cases of peripheral neuropathy are the only neurotoxicities reported. The authors report five additional cases of capecitabine-induced multifocal leukoencephalopathy.
卡培他滨用于治疗晚期乳腺癌和胃肠道恶性肿瘤。仅报告过1例脑病和3例周围神经病变这两种神经毒性反应。作者报告了另外5例由卡培他滨引起的多灶性白质脑病病例。
