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放射性相关静脉狭窄:血管内治疗选择

Radiation-associated venous stenosis: endovascular treatment options.

作者信息

Zhou Wei, Bush Ruth L, Lin Peter H, Lumsden Alan B

机构信息

Division of Vascular Surgery and Endovascular Therapy, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, The Methodist Hospital, Houston, TX 77030, USA.

出版信息

J Vasc Surg. 2004 Jul;40(1):179-82. doi: 10.1016/j.jvs.2004.03.039.

DOI:10.1016/j.jvs.2004.03.039
PMID:15218482
Abstract

We report a case of radiation-induced venous stenosis after pelvic irradiation to treat Paget's disease of the scrotum. During therapeutic anticoagulation, significant left lower extremity swelling developed due to an iliofemoral deep venous thrombosis (DVT). After percutaneous thrombectomy and thrombolysis, a high-grade stenosis was uncovered in the left external iliac vein, which was treated with an endoluminal stent. However, ipsilateral DVT recurred 2 months later despite continued anticoagulation therapy. Repeat treatment was successful. Pelvic radiation is a potential cause of iliac vein stenosis. Pharmacomechanical thrombectomy may have a useful role in management of complex iliofemoral DVT.

摘要

我们报告一例因盆腔放疗治疗阴囊佩吉特病后发生放射性静脉狭窄的病例。在治疗性抗凝期间,因髂股深静脉血栓形成(DVT)出现了明显的左下肢肿胀。经皮血栓切除术和溶栓治疗后,发现左髂外静脉存在高度狭窄,遂采用腔内支架进行治疗。然而,尽管持续进行抗凝治疗,同侧DVT在2个月后复发。再次治疗取得成功。盆腔放疗是髂静脉狭窄的一个潜在原因。药物机械性血栓切除术在复杂髂股DVT的管理中可能具有重要作用。

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