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一项使用关联维数对阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者呼吸运动进行日间简短测试。

A short daytime test using correlation dimension for respiratory movement in OSAHS.

作者信息

Miyata M, Burioka N, Sako T, Suyama H, Fukuoka Y, Tomita K, Higami S, Shimizu E

机构信息

Division of Medical Oncology and Molecular Respirology, Faculty of Medicine, Tottori University, Yonago, Japan.

出版信息

Eur Respir J. 2004 Jun;23(6):885-90. doi: 10.1183/09031936.04.00044104.

Abstract

In order to examine the pathology in patients with obstructive sleep apnoea/hypopnoea syndrome (OSAHS), the nonlinear properties of respiratory movement and breath-to-breath variations during resting wakefulness with eyes closed was investigated. Recording of the respiratory movement using inductive plethysmography was performed on 14 patients with OSAHS and 13 control subjects for 2 h in the supine position during daytime. To calculate the correlation dimension (D2) for respiratory movement, an algorithm proposed by Grassberger and Procaccia was applied. The indices of breath-to-breath variations were estimated. To calculate D2 and breath-to-breath variations, two different segments were selected (200 s each). The value of D2 for respiratory movement in patients with OSAHS was significantly greater than that in control subjects. In the case of > or = 2.0 of D2 for respiratory movement, the sensitivity and specificity of detecting the presence of OSAHS was 85.7% and 76.9%, respectively. On the basis of breath-to-breath variations, only the coefficient of variation of expiratory time for respiratory movement in patients with OSAHS was significantly greater than that in the control subjects. In conclusion, the measurements of correlation dimensions for respiratory movement with a brief period during wakefulness may be a useful index for identifying patients with obstructive sleep apnoea/hypopnoea syndrome.

摘要

为了研究阻塞性睡眠呼吸暂停/低通气综合征(OSAHS)患者的病理情况,我们对14例OSAHS患者和13名对照者在白天仰卧位闭眼静息状态下的呼吸运动非线性特性及逐次呼吸变化进行了研究。采用感应式体积描记法记录呼吸运动,持续2小时。为计算呼吸运动的关联维数(D2),应用了Grassberger和Procaccia提出的算法,并估算了逐次呼吸变化指标。计算D2和逐次呼吸变化时,选取了两个不同的时段(各200秒)。OSAHS患者呼吸运动的D2值显著高于对照者。当呼吸运动的D2值≥2.0时,检测OSAHS存在的敏感性和特异性分别为85.7%和76.9%。基于逐次呼吸变化,仅OSAHS患者呼吸运动呼气时间的变异系数显著高于对照者。总之,在清醒状态下短时间内测量呼吸运动的关联维数可能是识别阻塞性睡眠呼吸暂停/低通气综合征患者的有用指标。

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