Choi Nag- Jin, Kwon Daehyeon, Yun Suk Hoo, Jung Mun Yhung, Shin Hyun-Kyung
Division of Life Sciences and Silver Biotechnology Research Center, Hallym University, Chunchon, Kangwon-do 200-702, South Korea.
J Nutr Biochem. 2004 Jul;15(7):411-7. doi: 10.1016/j.jnutbio.2003.12.002.
The present study examined effects of a selectively hydrogenated soybean oil (SHSO) containing about 21% CLA on body composition, adipose depots and organ weights, and plasma lipid profiles in rats. Male Sprague Dawley rats were fed for 6 weeks a purified diet containing 0%, 1%, 3%, and 5% of SHSO. Different levels of SHSO supplementation did not significantly affect growth performance, although there was a trend toward decreased body weight gain with increasing dietary SHSO levels. The weights of inguinal, epididymal, and retroperitoneal adipose depot, but not mesenteric, were significantly influenced by dietary SHSO supplementation (P < 0.05, P < 0.01 and P < 0.001, respectively). Although the absolute weight of body protein in the control rats was higher in SHSO-fed rats, the effect on absolute weight of body protein is diluted and eliminated when the data are adjusted for eviscerated carcass weight as a percentage base. Therefore, as dietary SHSO level increased, body protein as a percentage of carcass weight increased (P < 0.05), although as dietary SHSO level increased, body fat proportion in carcass decreased (P < 0.01). Plasma triglycerides (TG) and total cholesterol (TC) concentrations were beneficially decreased, and HDL-cholesterol (HDL-C) to TC ratio was also beneficially increased by SHSO supplementation (P < 0.05, P < 0.001, and P < 0.01, respectively). However, plasma HDL-C concentration undesirably decreased with dietary SHSO supplementation (P < 0.05). The present study observed that body composition and plasma lipids were beneficially modulated by SHSO supplementation at least 3% levels (0.6% of CLA), and suggested that SHSO is a useful fat source because of the high level of CLA.
本研究检测了一种含有约21%共轭亚油酸（CLA）的选择性氢化大豆油（SHSO）对大鼠身体组成、脂肪储存、器官重量及血浆脂质谱的影响。将雄性斯普拉格-道利大鼠喂食含0%、1%、3%和5% SHSO的纯化饮食6周。不同水平的SHSO补充对生长性能没有显著影响，尽管随着饮食中SHSO水平的增加，体重增加有下降趋势。饮食中补充SHSO显著影响腹股沟、附睾和腹膜后脂肪储存的重量，但对肠系膜脂肪储存重量无显著影响（分别为P < 0.05、P < 0.01和P < 0.001）。虽然喂食SHSO的大鼠体内蛋白质的绝对重量高于对照大鼠，但当以去内脏胴体重量为百分比基数对数据进行调整后，对体内蛋白质绝对重量的影响被稀释并消除。因此，随着饮食中SHSO水平的增加，胴体重量中身体蛋白质的百分比增加（P < 0.05），尽管随着饮食中SHSO水平的增加，胴体中身体脂肪比例下降（P < 0.01）。补充SHSO可使血浆甘油三酯（TG）和总胆固醇（TC）浓度有益降低，HDL-胆固醇（HDL-C）与TC的比值也有益增加（分别为P < 0.05、P < 0.001和P < 0.01）。然而，饮食中补充SHSO会使血浆HDL-C浓度出现不利下降（P < 0.05）。本研究观察到，至少3%水平（CLA含量为0.6%）的SHSO补充可有益调节身体组成和血浆脂质，并表明由于CLA含量高，SHSO是一种有用的脂肪来源。
