Menezes Luciane M, Campos Luis C, Quintão Catia C, Bolognese Ana M
Pontifical Catholic University of Rio Grande do Sul-PUCRS, Rua Vicente da Fontoura, 2199/402, Santa Cecilia, Porto Alegre/RS CEP: 90.640-003, Brazil.
Am J Orthod Dentofacial Orthop. 2004 Jul;126(1):58-64. doi: 10.1016/j.ajodo.2003.05.014.
To study the incidence of hypersensitivity to orthodontic metals, patch tests were carried out before and 2 months after the placement of orthodontic appliances in 38 patients (17 male, 21 female). The tested substances were cobalt chloride, copper sulfate, potassium dichromate, iron sulfate, manganese chloride, molybdenum salt, nickel sulfate, and titanium oxide. Eight strips containing the test substances were positioned on the patients' backs. They were removed after 48 hours and assessed by a dermatologist at 48 and 72 hours after antigen application. The obtained data were analyzed by the chi-square test and McNemar's chi-square test. Statistically significant positive reactions were observed for nickel sulfate (21.1%), potassium dichromate (21.1%), and manganese chloride (7.9%); reactions to nickel sulfate had the greatest intensity. No differences were observed between the reactions before and after placement of the orthodontic appliances; this indicates that they did not sensitize the patients or affect their tolerance to these metals during the study period. No statistical difference was observed regarding sex for any evaluated substance, although a greater tendency to positivity to nickel sulfate was observed among female patients and to potassium dichromate in male patients.
为研究对正畸金属过敏的发生率，对38例患者（17例男性，21例女性）在佩戴正畸矫治器前及佩戴后2个月进行了斑贴试验。受试物质为氯化钴、硫酸铜、重铬酸钾、硫酸亚铁、氯化锰、钼盐、硫酸镍和氧化钛。将含有受试物质的8条试纸条贴于患者背部。48小时后取下，在施加抗原后48小时和72小时由皮肤科医生进行评估。所得数据采用卡方检验和McNemar卡方检验进行分析。观察到硫酸镍（21.1%）、重铬酸钾（21.1%）和氯化锰（7.9%）有统计学意义的阳性反应；对硫酸镍的反应强度最大。在佩戴正畸矫治器前后的反应之间未观察到差异；这表明在研究期间它们未使患者致敏或影响其对这些金属的耐受性。对于任何评估物质，在性别方面未观察到统计学差异，尽管女性患者对硫酸镍呈阳性的倾向更大，而男性患者对重铬酸钾呈阳性的倾向更大。
