前交叉韧带重建中的增强——山羊的组织学和生物力学研究
Augmentation in anterior cruciate ligament reconstruction-a histological and biomechanical study on goats.
作者信息
Buma P, Kok H J, Blankevoort L, Kuijpers W, Huiskes R, Van Kampen A
机构信息
Orthopaedic Research Laboratory, Institute of Orthopaedics, UMCN, PO Box 9101, 6500 HB, Nijmegen, The Netherlands.
出版信息
Int Orthop. 2004 Apr;28(2):91-6. doi: 10.1007/s00264-003-0515-0. Epub 2003 Nov 11.
Abstract
We studied reconstruction of the anterior cruciate ligament (ACL) in skeletally mature goats. In one group, the autogenous tissue was augmented with polydioxanone (PDS), the other group had no augmentation. Histological complete incorporation and remodeling of the transplant was found in both groups. The newly formed connective tissues gradually assumed the microscopic properties of the normal ligament. The augmented group showed a delay in remodeling and maturation of the fiber bundles. Mechanically, the PDS-augmented transplants were stronger than the nonaugmented transplants immediately after surgery. During the first 6 weeks, a rapid decrease in strength of the augmented transplants was found, whereas the strength of the nonaugmented group gradually increased. The results of our experiment do not favor augmentation of autografts in reconstruction of the ACL.
摘要
我们研究了骨骼成熟山羊前交叉韧带（ACL）的重建。一组用聚二氧六环酮（PDS）增强自体组织，另一组不进行增强。两组均发现移植组织在组织学上完全整合并重塑。新形成的结缔组织逐渐具备正常韧带的微观特性。增强组的纤维束重塑和成熟出现延迟。在力学方面，PDS增强的移植组织在术后即刻比未增强的移植组织更强。在最初6周内，增强移植组织的强度迅速下降，而未增强组的强度逐渐增加。我们的实验结果不支持在ACL重建中增强自体移植物。
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