Hurria Arti, Kris Mark G
Memorial Sloan-Kettering Cancer Center, Weill Medical College of Cornell University, New York, NY, USA.
CA Cancer J Clin. 2003 Nov-Dec;53(6):325-41. doi: 10.3322/canjclin.53.6.325.
Lung cancer is the leading cause of cancer death in the United States. At the time of diagnosis, most patients are older than 65 years and have Stage III or IV disease. More than 80% of patients have non-small cell lung cancer and the rest have small cell lung cancer. Age is not a significant prognostic factor for overall survival and response to treatment for patients with either type of lung cancer. Treatment options should be tailored to older patients based on the same selection process and benefits seen in the population as a whole. This article reviews the available data regarding surgery, radiation, and systemic treatment for older patients with lung cancer and considers the role of geriatric assessment in the evaluation of older patients.
肺癌是美国癌症死亡的主要原因。在确诊时,大多数患者年龄超过65岁,患有III期或IV期疾病。超过80%的患者患有非小细胞肺癌,其余患者患有小细胞肺癌。年龄对于这两种类型肺癌患者的总生存期和治疗反应而言并非重要的预后因素。应根据整个群体中相同的选择过程和益处,为老年患者量身定制治疗方案。本文回顾了有关老年肺癌患者手术、放疗和全身治疗的现有数据,并探讨了老年评估在老年患者评估中的作用。