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老年肺癌患者的评估与管理。

Evaluation and management of elderly patients with lung cancer.

机构信息

Department of Radiation Oncology, Medical College of Wisconsin Milwaukee, WI 53226, USA.

出版信息

Semin Radiat Oncol. 2012 Oct;22(4):304-10. doi: 10.1016/j.semradonc.2012.05.007.

DOI:10.1016/j.semradonc.2012.05.007
PMID:22985813
Abstract

Most patients diagnosed with lung cancer are older than 65 years. Advancing age is associated with increased medical and psychosocial issues that increase the complexity of care. This article provides a summary and update of work-up and management of elderly patients with lung cancer. Patient-related prognostic factors with attention to assessment of comorbidity in lung cancer patients are reviewed. Recent literature regarding toxicity and advances in locoregional and systemic therapies are reviewed, with recommendations for management.

摘要

大多数被诊断患有肺癌的患者年龄都在 65 岁以上。随着年龄的增长,与医疗和心理社会问题相关的问题也会增加,这增加了护理的复杂性。本文提供了老年肺癌患者的检查和管理的总结和更新。本文回顾了与患者相关的预后因素,重点是评估肺癌患者的合并症。本文还回顾了有关毒性和局部区域及全身治疗进展的最新文献,并提出了治疗建议。

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引用本文的文献

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Surgery offers survival advantage over radiotherapy in patients who are 80 years and older with Stage I and II NSCLC: A retrospective cohort study of 7,045 patients.对于80岁及以上的I期和II期非小细胞肺癌患者,手术治疗比放射治疗具有生存优势:一项对7045例患者的回顾性队列研究。
Front Surg. 2022 Oct 4;9:1018320. doi: 10.3389/fsurg.2022.1018320. eCollection 2022.
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Construction of a Nomogram for Predicting Survival in Elderly Patients With Lung Adenocarcinoma: A Retrospective Cohort Study.用于预测老年肺腺癌患者生存的列线图构建:一项回顾性队列研究
Front Med (Lausanne). 2021 Jul 14;8:680679. doi: 10.3389/fmed.2021.680679. eCollection 2021.
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Is the Outcome of Pulmonary Resections due to Non-Small Cell Lung Cancer in Octogenarian Patients Worse?
老年患者因非小细胞肺癌行肺切除术后的结局更差吗?
Ann Thorac Cardiovasc Surg. 2019 Apr 20;25(2):95-101. doi: 10.5761/atcs.oa.18-00206. Epub 2018 Dec 11.
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Analysis of the characteristics and prognosis of advanced non-small-cell lung cancer in older patients.老年晚期非小细胞肺癌患者的特征及预后分析
Patient Prefer Adherence. 2015 Aug 19;9:1189-94. doi: 10.2147/PPA.S87069. eCollection 2015.
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Causal effects of time-dependent treatments in older patients with non-small cell lung cancer.老年非小细胞肺癌患者时间依赖性治疗的因果效应。
PLoS One. 2015 Apr 7;10(4):e0121406. doi: 10.1371/journal.pone.0121406. eCollection 2015.
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Cardiovascular comorbidities and survival of lung cancer patients: Medicare data based analysis.心血管合并症与肺癌患者的生存率:基于医疗保险数据的分析
Lung Cancer. 2015 Apr;88(1):85-93. doi: 10.1016/j.lungcan.2015.01.006. Epub 2015 Jan 17.