Turk Dennis C, Dworkin Robert H
Department of Anesthesiology, University of Washington, Seattle, Washington, USA.
Arthritis Res Ther. 2004;6(4):151-4. doi: 10.1186/ar1196. Epub 2004 Jun 4.
A consensus conference with representatives from academia, governmental agencies, and the pharmaceutical industry met and concluded that clinical trials designed to assess the efficacy and effectiveness of treatments for chronic pain should consider outcomes in six core domains: pain, physical functioning, emotional functioning, patient global ratings of satisfaction, negative health states and adverse events, and patient disposition. In addition, it was acknowledged that there are many secondary domains that might be of importance and should be included in trials depending on the nature of the treatment and population to whom the treatment is targeted.
一场由来自学术界、政府机构和制药行业的代表参加的共识会议召开并得出结论：旨在评估慢性疼痛治疗效果和有效性的临床试验应考虑六个核心领域的结果，即疼痛、身体功能、情绪功能、患者总体满意度、负面健康状况和不良事件，以及患者处置情况。此外，会议承认，根据治疗的性质和治疗所针对的人群，还有许多可能重要的次要领域，应纳入试验。
