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高龄初产妇的产科风险

Obstetrical risks in the older primigravida.

作者信息

Naqvi Mehreen Mehdi, Naseem Azra

机构信息

Department of Obstetrics and Gynaecology, POF Hospital, Wah Cantt.

出版信息

J Coll Physicians Surg Pak. 2004 May;14(5):278-81.

Abstract

OBJECTIVE

To compare the complications, delivery mode and fetal outcome between elderly primigravidae and young primigravidae.

DESIGN

A comparative study.

PLACE AND DURATION OF STUDY

Department of Obstetrics and Gynaecology, POFs Hospital, Wah Cantt, from January 2001 to December 2002.

SUBJECTS AND METHODS

One hundred and fifty six elderly primigravidae were compared with a matched pair group of younger primigravidae regarding antenatal, intrapartum and postpartum complications. Perinatal mortality was also compared. Specially designed proforma was used to record the information. Data analysis was performed using SPSS package for windows version 10.0. Results were compared using Chi-square test by keeping the p-value of <0.05 as significant.

RESULTS

Amongst the complications during pregnancy, pregnancy induced hypertension was commonest complication in elderly primigravidas (24.35% vs. 6.41%, p-value < 0.05). Diabetes, malpresentation and premature labour were also more frequent in elderly group (p-value < 0.05). More (30.76%) of elderly group were delivered by caesarean section as compared to 16.02% in young group (p-value < 0.05). Congenital malformations of the fetus were common in elderly group (5.12% vs. 1.28%). Cases of essential hypertension (12.82% vs. 1.92%), fibroid uterus (9.61% vs 2.56%) and ovarian cyst (7.69% vs. 1.92%) were frequent in elderly group patients. Perinatal mortality was relatively high in elderly groups and compared to young patients and 17 babies in elderly group were still born as compared to 10 babies in young group.

CONCLUSION

Advanced maternal age has been associated with an increased risk of various complications like hypertension, diabetes, and intrauterine growth retardation and congenital malformations. Timely and accurately diagnosis of complications and their treatment leads to favorable outcome. The higher rate of caesarean section in older primigravidas is due mainly to higher rate of obstetrical complications.

摘要

目的

比较高龄初产妇和年轻初产妇的并发症、分娩方式及胎儿结局。

设计

一项对比研究。

研究地点及时间

瓦赫坎特POFs医院妇产科,2001年1月至2002年12月。

研究对象与方法

将156例高龄初产妇与一组年龄匹配的年轻初产妇在产前、产时及产后并发症方面进行比较。同时比较围产期死亡率。使用专门设计的表格记录信息。采用SPSS 10.0 for windows软件包进行数据分析。采用卡方检验比较结果,将p值<0.05视为具有显著性。

结果

在孕期并发症中,高龄初产妇最常见的并发症是妊娠期高血压(24.35%对6.41%,p值<0.05)。糖尿病、胎位异常及早产在高龄组中也更为常见(p值<0.05)。高龄组剖宫产率更高(30.76%),而年轻组为16.02%(p值<0.05)。胎儿先天性畸形在高龄组中更为常见(5.12%对1.28%)。高龄组患者原发性高血压(12.82%对1.92%)、子宫肌瘤(9.61%对2.56%)及卵巢囊肿(7.69%对1.92%)的病例更为常见。高龄组围产期死亡率相对较高,高龄组有17例死产,而年轻组有10例。

结论

高龄产妇与高血压、糖尿病、胎儿宫内生长受限及先天性畸形等各种并发症风险增加有关。及时、准确地诊断并发症并进行治疗可带来良好结局。高龄初产妇剖宫产率较高主要是由于产科并发症发生率较高。

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