1900年至2003年黄热病和登革热流行病学的变化：兜了一圈又回到原点？
The changing epidemiology of yellow fever and dengue, 1900 to 2003: full circle?
作者信息
Gubler D J
机构信息
Asia-Pacific Institute of Tropical Medicine and Infectious Diseases, John A. Burns School of Medicine, University of Hawaii at Manoa, 3675 Kilauea Avenue, Leahi Hospital, Honolulu, HI 96816, USA.
出版信息
Comp Immunol Microbiol Infect Dis. 2004 Sep;27(5):319-30. doi: 10.1016/j.cimid.2004.03.013.
Yellow fever and dengue are old diseases, having caused major epidemics in centuries past. Both were effectively controlled in the mid 1900s, yellow fever in Francophone Africa by vaccination and yellow fever and dengue in the Americas by effective control of the principal urban vector of both viruses, Aedes aegypti. In the last 25 years of the 20th century, however, there was a resurgence of yellow fever in Africa, and of dengue worldwide. The factors responsible for this resurgence are discussed, as are current options for prevention and control.
黄热病和登革热是古老的疾病，在过去几个世纪曾引发重大疫情。20世纪中叶，这两种疾病都得到了有效控制，在非洲法语国家，通过接种疫苗控制了黄热病；在美洲，通过有效控制这两种病毒的主要城市病媒埃及伊蚊，控制了黄热病和登革热。然而，在20世纪的最后25年里，非洲的黄热病疫情再度出现，登革热则在全球范围内卷土重来。本文讨论了导致疫情再度出现的因素以及当前的预防和控制措施。
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