Matzinger M A, Briggs V A, Dunlap H J, Udjus K, Martin D J, McDonald P
Department of Radiology, Children's Hospital of Eastern Ontario, Ottawa, Canada.
Pediatr Radiol. 1992;22(4):264-6. doi: 10.1007/BF02019854.
Prostaglandin E1 intravenous infusion is used in infants with ductal-dependent congenital heart disease to maintain ductal patency and prolong life until palliative or corrective surgery is feasible. Complications of prostaglandin administration include fever, diarrhoea, hypotension, apnoea, bradycardia, pseudowidening of the cranial sutures, underossification of the calvarial bones, periostitis, and skin edema [1-3]. This paper presents dramatic plain radiographic features of prostaglandin-induced bone disease, including periosteal proliferation and the unusual bone-within-bone appearance, and provides the previously unpublished CT correlation.
前列腺素E1静脉输注用于患有依赖动脉导管的先天性心脏病的婴儿，以维持动脉导管通畅并延长生命，直至可行姑息性或矫正性手术。使用前列腺素的并发症包括发热、腹泻、低血压、呼吸暂停、心动过缓、颅骨缝线假性增宽、颅骨骨化不足、骨膜炎和皮肤水肿[1-3]。本文介绍了前列腺素诱导的骨病显著的平片影像学特征，包括骨膜增生和罕见的骨中骨表现，并提供了此前未发表的CT相关性。
