Beitzke A, Stein J
Pediatr Radiol. 1986;16(1):57-8. doi: 10.1007/BF02387508.
Disturbance of desmogenous ossification of the skull is an extremely rare complication of long-term prostaglandin treatment. This report describes a newborn with pulmonary atresia, ventricular septal defect and ductus-dependent pulmonary blood flow in whom administration of prostaglandin E1 (PGE1) over a period of 96 days produced uncommon clinical and radiologic findings.
颅骨骨源性骨化紊乱是长期使用前列腺素治疗极为罕见的并发症。本报告描述了一名患有肺动脉闭锁、室间隔缺损和动脉导管依赖性肺血流的新生儿，其接受前列腺素E1（PGE1）治疗96天，出现了罕见的临床和放射学表现。
