Azev Viatcheslav N, D'Alarcao Marc
Department of Chemistry, Tufts University, 62 Talbot Avenue, Medford, Massachusetts 02155, USA.
J Org Chem. 2004 Jul 9;69(14):4839-42. doi: 10.1021/jo049521l.
A method for the synthesis of chiral 1,2-diamino-1,2-dideoxy-myo-inositol-based bis-pyridyl ligands 3a and 3b from the corresponding myo-inositol precursor is described. These highly functionalized inosamine-bis-pyridyl ligands are expected to provide a useful platform for exploring the relationship between chiral ligand structure and enantioselective olefin oxidation catalyzed by their metal complexes.
描述了一种从相应的肌醇前体合成手性1,2-二氨基-1,2-二脱氧-肌醇基双吡啶配体3a和3b的方法。这些高度官能化的肌醇胺-双吡啶配体有望为探索手性配体结构与其金属配合物催化的对映选择性烯烃氧化之间的关系提供一个有用的平台。
