Lee Sung Wook, Lee Kooyeon, Seomoon Dong, Kim Sundae, Kim Hyunseok, Kim Hyun, Shim Eunkyong, Lee Miae, Lee Seokju, Kim Misook, Lee Phil Ho
Department of Chemistry, Kangwon National University, Chunchon 200-701, Republic of Korea.
J Org Chem. 2004 Jul 9;69(14):4852-5. doi: 10.1021/jo0495790.
Tetraorganoindates, which were prepared easily from the reaction of 1 equiv of InCl(3) with 4 equiv of organometallics, could be employed as effective nucleophilic cross-coupling partners in Pd-catalyzed carbonylative cross-coupling reactions with a variety of organic electrophiles. The present method gave unsymmetrical ketones and 1,4-diacylbenzenes in good yields with highly efficient transfer of almost all the organic groups attached to the indium under a carbon monoxide atmosphere in THF at 60 degrees C.
四有机铟酸盐可通过 1 当量的 InCl₃ 与 4 当量的有机金属化合物反应轻松制备，在钯催化的与各种有机亲电试剂的羰基化交叉偶联反应中，它可用作有效的亲核交叉偶联伙伴。在 60℃的一氧化碳气氛下于四氢呋喃中，该方法能以良好的产率得到不对称酮和 1,4 - 二酰基苯，几乎所有连接在铟上的有机基团都能高效转移。
