Gottesman Susan
Laboratory of Molecular Biology, National Cancer Institute, Bethesda, MD 20892, USA.
Cell. 2004 Jul 9;118(1):1-2. doi: 10.1016/j.cell.2004.06.024.
Small regulatory RNAs can act by pairing with their target messages, targeting themselves and the mRNA for degradation; Lenz et al. (this issue of Cell) now report that multiple small RNAs are essential regulators of the quorum-sensing systems of Vibrio species, including the regulation of virulence in V. cholerae.
小调节RNA可通过与它们的靶标信使RNA配对发挥作用,使自身和信使RNA靶向降解;伦茨等人(本期《细胞》)现报道,多种小RNA是弧菌属群体感应系统的重要调节因子,包括对霍乱弧菌毒力的调节。