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采用电感耦合等离子体质谱法测定硅胶乳房植入物材料和包膜组织中的铂浓度。

Platinum concentration in silicone breast implant material and capsular tissue by ICP-MS.

作者信息

Maharaj S V M

机构信息

Department of Chemistry, American University, Washington, DC 20016, USA.

出版信息

Anal Bioanal Chem. 2004 Sep;380(1):84-9. doi: 10.1007/s00216-004-2714-y. Epub 2004 Jul 8.

DOI:10.1007/s00216-004-2714-y
PMID:15243733
Abstract

Inductively coupled plasma-mass spectrometry (ICP-MS) was used to determine the concentration of platinum (Pt) in silicone breast implant gel (range, 0.26-48.90 microg g(-1) Pt; n=15), elastomer (range, 3.05-28.78 microg g(-1) Pt; n=7), double lumen (range, 5.79-125.27 microg g(-1) Pt; n=7), foam (range, 5.79-8.36 microg g(-1) Pt; n=2), and capsular tissue (range, 0.003-0.272 microg g(-1) Pt; n=15). The results show that very high levels of Pt are present in the encasing elastomer, double lumen, and foam envelope materials. Silicone breast implants can be a source of significant Pt exposure for individuals with these implants.

摘要

采用电感耦合等离子体质谱法(ICP-MS)测定硅凝胶乳房植入物凝胶中铂(Pt)的浓度(范围为0.26 - 48.90微克/克铂;n = 15)、弹性体(范围为3.05 - 28.78微克/克铂;n = 7)、双腔(范围为5.79 - 125.27微克/克铂;n = 7)、泡沫(范围为5.79 - 8.36微克/克铂;n = 2)以及包膜组织(范围为0.003 - 0.272微克/克铂;n = 15)中的铂浓度。结果表明,包裹性弹性体、双腔和泡沫包膜材料中存在非常高含量的铂。对于植入这些硅凝胶乳房植入物的个体而言,硅凝胶乳房植入物可能是铂暴露的一个重要来源。

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