Niggli Hugo J
BioFoton AG, P.O. Box 28, CH-1731 Ependes, Switzerland.
Indian J Exp Biol. 2003 May;41(5):419-23.
Yield of ultraweak photon emission in a cell culture model for biophotonic measurements using fibroblastic differentiation depended on the temperature of photonic measurement. The ultraweak photon emission of medium was significantly higher at 37 degrees C than at 25 degrees C and after UVB-irradiation this difference was even more pronounced. While with cells in the medium no temperature dependence could be determined in unirradiated samples, after UVB-irradiation of cells an increase of biophotonic emission was observed in postmitotic fibroblasts. While after several UVB exposures normal cells begin to absorb the ultraviolet light, cells from patients with the disease Xeroderma Pigmentosum loose this capacity. In view that fibroblasts play an essential role in skin aging, skin carcinogenesis and wound healing, the biophotonic model using the fibroblastic differentiation system provides to be a new and powerful non-invasive tool for the development of skin science.
在使用成纤维细胞分化进行生物光子测量的细胞培养模型中，超微弱光子发射的产量取决于光子测量的温度。培养基的超微弱光子发射在37摄氏度时显著高于25摄氏度，并且在紫外线B照射后这种差异更加明显。虽然在未照射的样品中，培养基中的细胞未表现出温度依赖性，但在对细胞进行紫外线B照射后，有丝分裂后的成纤维细胞中观察到生物光子发射增加。在多次紫外线B照射后，正常细胞开始吸收紫外线，而患有色素性干皮病的患者的细胞则丧失了这种能力。鉴于成纤维细胞在皮肤衰老、皮肤癌发生和伤口愈合中起着至关重要的作用，使用成纤维细胞分化系统的生物光子模型有望成为皮肤科学发展的一种新型强大的非侵入性工具。
