直肠内磁共振成像用于预测前列腺癌的肿瘤部位、肿瘤大小及局部浸润情况。

Endorectal MRI for prediction of tumor site, tumor size, and local extension of prostate cancer.

作者信息

Nakashima Jun, Tanimoto Akihiro, Imai Yutaka, Mukai Makio, Horiguchi Yutaka, Nakagawa Ken, Oya Mototsugu, Ohigashi Takashi, Marumo Ken, Murai Masaru

机构信息

Department of Urology, Keio University School of Medicine, Tokyo, Japan.

出版信息

Urology. 2004 Jul;64(1):101-5. doi: 10.1016/j.urology.2004.02.036.

DOI:10.1016/j.urology.2004.02.036

PMID:15245944

Abstract

OBJECTIVES

To assess the value of endorectal magnetic resonance imaging (MRI) for detecting the tumor site, tumor size, and disease extent in patients with localized prostate cancer.

METHODS

The MRI findings were compared with the histopathologic findings of radical prostatectomy specimens in 95 patients.

RESULTS

The histologic examination revealed 186 cancer foci. Endorectal MRI detected 109 cancer foci. The accuracy, sensitivity, and positive predictive value of endorectal MRI for detecting tumor foci greater than 1.0 cm in diameter was 79.8%, 85.3%, and 92.6%, respectively; the corresponding value for detecting tumor foci smaller than 1.0 cm was 24.2%, 26.2%, and 75.9%, respectively. The maximal tumor diameter on endorectal MRI correlated with that shown by histologic examination for tumors larger than 1.0 cm in diameter. However, it did not correlate significantly with the histologic diameter of tumors smaller than 1.0 cm. The accuracy, sensitivity, specificity, positive predictive value, and negative predictive value of endorectal MRI was 74.7%, 57.1%, 82.1%, 57.1%, and 82.1%, respectively, for the detection of extracapsular extension and was 75.8%, 62.1%, 81.8%, 60.0%, and 83.1%, respectively, for local staging.

CONCLUSIONS

The results of the present study suggest that endorectal MRI is useful for predicting local extension, as well as tumor site and tumor size, of cancer foci greater than 1.0 cm in diameter.

摘要

目的

评估直肠内磁共振成像（MRI）在检测局限性前列腺癌患者肿瘤部位、肿瘤大小及疾病范围方面的价值。

方法

将95例患者的MRI检查结果与前列腺癌根治术标本的组织病理学检查结果进行比较。

结果

组织学检查发现186个癌灶。直肠内MRI检测到109个癌灶。直肠内MRI检测直径大于1.0 cm的肿瘤灶的准确性、敏感性和阳性预测值分别为79.8%、85.3%和92.6%；检测直径小于1.0 cm的肿瘤灶的相应值分别为24.2%、26.2%和75.9%。直肠内MRI上的最大肿瘤直径与组织学检查显示的直径大于1.0 cm的肿瘤相关。然而，它与直径小于1.0 cm的肿瘤的组织学直径无显著相关性。直肠内MRI检测包膜外侵犯的准确性、敏感性、特异性、阳性预测值和阴性预测值分别为74.7%、57.1%、82.1%、57.1%和82.1%，局部分期的相应值分别为75.8%、62.1%、81.8%、60.0%和83.1%。