马波拉尔病毒，一种与委内瑞拉西部的黄褐侏鼠（黄褐稻鼠）相关的汉坦病毒。

Maporal virus, a hantavirus associated with the fulvous pygmy rice rat (Oligoryzomys fulvescens) in western Venezuela.

作者信息

Fulhorst Charles F, Cajimat Maria N B, Utrera Antonio, Milazzo Mary L, Duno Gloria M

机构信息

University of Texas Medical Branch, Galveston 77555-0609, USA.

出版信息

Virus Res. 2004 Sep 1;104(2):139-44. doi: 10.1016/j.virusres.2004.03.009.

DOI:10.1016/j.virusres.2004.03.009

PMID:15246651

Abstract

Oryzomine rodents in the southeastern United States, Panama, and southern South America are natural hosts of 6 of the 13 viruses known to cause hantavirus pulmonary syndrome. The purpose of this study was to extend our knowledge of the geographical distribution and genetic diversity of the hantaviruses associated with oryzomine rodents in South America. An infectious hantavirus was isolated from two fulvous pygmy rice rats captured in western Venezuela. Analyses of complete nucleocapsid protein and glycoprotein precursor sequences indicated that the isolates are strains of a novel hantavirus (proposed name "Maporal") which is phylogenetically most closely related to the viruses known to cause hantavirus pulmonary syndrome in southern South America.

摘要

在美国东南部、巴拿马和南美洲南部的稻鼠是已知可导致汉坦病毒肺综合征的13种病毒中6种病毒的天然宿主。本研究的目的是扩展我们对南美洲与稻鼠相关的汉坦病毒地理分布和遗传多样性的认识。从委内瑞拉西部捕获的两只黄褐小家鼠中分离出一种传染性汉坦病毒。对完整核衣壳蛋白和糖蛋白前体序列的分析表明，分离株是一种新型汉坦病毒（暂定名“马波拉尔”）的毒株，在系统发育上与已知在南美洲南部引起汉坦病毒肺综合征的病毒关系最为密切。