Mok Vincent C T, Wong Adrian, Yim Patty, Fu Michael, Lam Wynnie W M, Hui Andrew C, Yau Carmen, Wong Ka Sing
Departments of Medicine and Therapeutics, Chinese University of Hong Kong, Shatin, Hong Kong.
Alzheimer Dis Assoc Disord. 2004 Apr-Jun;18(2):68-74. doi: 10.1097/01.wad.0000126617.54783.7.
Frontal Assessment Battery (FAB) is a valid and reliable screening test for evaluating executive dysfunction among whites with frontal and subcortical degenerative lesions. We studied the properties of a Chinese version of FAB (CFAB) in evaluating executive dysfunction among Chinese stroke patients with small subcortical infarct.
Concurrent validity was evaluated using Wisconsin Card Sorting Tst (WCST) and Mattis Dementia Rating Scale-Initiation/Perseveration Subset (MDRS I/P) among 41 controls and 30 stroke patients with small subcortical infarct. Discriminant validities of CFAB and its subitems were compared with those of Mini-Mental State Examination (MMSE). Internal consistency, test-retest, and interrater reliability of CFAB were evaluated.
The CFAB had low to good correlation with various executive measures: MDRS I/P (r = 0.63, p < 0.001), number of category completed (r = 0.45, p < 0.001), and number of perseverative errors (r = -0.37, p < 0.01) of WCST. Among the executive measures, only number of category completed had significant but small contribution (6.5%, p = 0.001) to the variance of CFAB. A short version of CFAB using three items yielded higher overall classification accuracy (86.6%) than that of CFAB full version (80.6%) and MMSE (77.6%). Internal consistency (alpha = 0.77), test-retest reliability (rho = 0.89, p < 0.001), and interrater reliability (rho = 0.85, p < 0.001) of CFAB were good.
Although CFAB is reliable, it is only moderately valid in evaluating executive dysfunction among Chinese stroke patients with small subcortical infarct. The clinical use of CFAB in the evaluation of executive dysfunction among this group of patients cannot be recommended at this stage.
额叶评估量表(FAB)是一种有效且可靠的筛查测试,用于评估患有额叶和皮质下退行性病变的白人的执行功能障碍。我们研究了中文版FAB(CFAB)在评估患有皮质下小梗死的中国中风患者执行功能障碍方面的特性。
在41名对照者和30名患有皮质下小梗死的中风患者中,使用威斯康星卡片分类测试(WCST)和马蒂斯痴呆评定量表-启动/持续性子量表(MDRS I/P)评估同时效度。将CFAB及其子项目的区分效度与简易精神状态检查表(MMSE)的区分效度进行比较。评估CFAB的内部一致性、重测信度和评分者间信度。
CFAB与各种执行功能测量指标的相关性从低到高:MDRS I/P(r = 0.63,p < 0.001)、WCST完成的类别数(r = 0.45,p < 0.001)和持续错误数(r = -0.37,p < 0.01)。在执行功能测量指标中,只有完成的类别数对CFAB的方差有显著但较小的贡献(6.5%,p = 0.001)。使用三个项目的CFAB简版产生的总体分类准确率(86.6%)高于CFAB完整版(80.6%)和MMSE(77.6%)。CFAB的内部一致性(α = 0.77)、重测信度(ρ = 0.89,p < 0.001)和评分者间信度(ρ = 0.85,p < 0.001)良好。
尽管CFAB可靠,但在评估患有皮质下小梗死的中国中风患者的执行功能障碍方面仅具有中等效度。现阶段不建议在该组患者的执行功能障碍评估中临床使用CFAB。