Karaulov A W, Frasch V N
Allerg Immunol (Leipz). 1978;24(3):194-8.
Changes in T-and B-lymphocytes content in experimental benzene intotication (BI) of CBA-mice were studied. The content of spontaneously rosette-forming cells, B-lymphocytes with C3 -receptors and T-cells in macro-and microtest was determined. It was shown that BI resulted in disorders in the function of thymus, depression of T-cell system and autoimmune shifts. A number of characteristics in kinetics of various fractions of lymphoid cells due perhaps, to different sensitivity of particular types of lymphoid cells to benzene and compensatory response as well. The significance of described phenomena is discussed.
研究了CBA小鼠实验性苯中毒(BI)时T淋巴细胞和B淋巴细胞含量的变化。测定了大体和微观试验中自发形成玫瑰花结细胞、具有C3受体的B淋巴细胞和T细胞的含量。结果表明,苯中毒导致胸腺功能紊乱、T细胞系统抑制和自身免疫性改变。淋巴细胞不同亚群动力学的一些特征,可能是由于特定类型的淋巴细胞对苯的敏感性不同以及代偿反应所致。文中讨论了上述现象的意义。