吸烟会延迟骨愈合：一项对200例采用半骨骺牵伸技术手术患者的前瞻性研究。
Cigarette smoking delays bone healing: a prospective study of 200 patients operated on by the hemicallotasis technique.
作者信息
W-Dahl Annette, Toksvig-Larsen Sören
机构信息
Department of Orthopedics, University Hospital, Lund, Sweden.
出版信息
Acta Orthop Scand. 2004 Jun;75(3):347-51. doi: 10.1080/00016470410001303.
BACKGROUND
Cigarette smoking is known to impede bone healing. The hemicallotasis technique is based on an external fixation and delayed healing prolongs treatment and increases the risk of further complications.
PATIENTS AND METHODS
200 patients, 34 smokers and 166 nonsmokers, operated on by the hemicallotasis technique in the proximal tibia for deformities of the knee (knee arthrosis in 186 patients) were consecutively studied. We recorded their preoperative smoking habits, postoperative complications and the duration of treatment with external fixation.
RESULTS
Half of the smokers and one fifth of the nonsmokers developed complications. Their mean time in external fixation was 96 (SD 20) days. Smokers required an average of 16 days more in external fixation. Delayed healing and pseudoarthrosis were commoner in smokers than nonsmokers. The risk ratio for smokers to develop complications was 2.5, as compared to nonsmokers.
背景
众所周知，吸烟会妨碍骨折愈合。半骺延长术基于外固定技术，而延迟愈合会延长治疗时间并增加进一步出现并发症的风险。
患者与方法
连续研究了200例采用半骺延长术治疗胫骨近端畸形（186例为膝关节骨性关节炎）的患者，其中34例吸烟者，166例不吸烟者。记录了他们术前的吸烟习惯、术后并发症以及外固定治疗的持续时间。
结果
一半的吸烟者和五分之一的不吸烟者出现了并发症。他们接受外固定的平均时间为96（标准差20）天。吸烟者在外固定方面平均需要多16天。延迟愈合和假关节在吸烟者中比不吸烟者更为常见。与不吸烟者相比，吸烟者发生并发症的风险比为2.5。
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