Onderoglu Lütfü S, Gültekin Murat, Dursun Polat, Karcaaltincaba Musturay, Usubutun Alp, Akata Deniz, Ayhan Ali
Department of Obstetrics and Gynecology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Gynecol Oncol. 2004 Jul;94(1):223-5. doi: 10.1016/j.ygyno.2004.03.042.
Ovarian fibromatosis is a very rare nonneoplastic disease. Due to the rarity and atypical clinical presentations, they may give rise to a misdiagnosis of malignancy and unnecessary extensive surgical interventions. Literature lacks definitive data about this rare disease and its preoperative evaluations. MRI together with the intraoperative frozen section may help us to define the benign nature of the disease. In this report, we aimed to review the literature and give a highlight to the gynecologic oncologists about this rare disease.
A 19-year-old female patient admitted to our hospital with the complaints of menstrual irregularity, hirsutism, and increased abdominal girth. Physical examination revealed bilateral ovarian mass, hirsutism, and ascites. Serum CA-125 levels were slightly elevated. Preoperative MRI study showed bilateral hypointense lobulated ovarian masses. With the initial diagnosis of ovarian tumor, we performed explorative laparotomy and excised both masses. Final pathology was reported as bilateral ovarian fibromatosis.
Ovarian fibromatosis commonly presents with ascites and solid pelvic mass and can be misdiagnosed as a malignant ovarian tumor. In young patients, clinicians should consider ovarian fibromatosis in differential diagnosis of pelvic mass. Preoperative MRI findings and intraoperative frozen examination may be used to avoid unnecessary aggressive surgical management.
卵巢纤维瘤病是一种非常罕见的非肿瘤性疾病。由于其罕见性和不典型的临床表现，可能会导致恶性肿瘤的误诊以及不必要的广泛手术干预。文献中缺乏关于这种罕见疾病及其术前评估的确切数据。磁共振成像（MRI）结合术中冰冻切片可能有助于我们确定该疾病的良性性质。在本报告中，我们旨在回顾文献，并向妇科肿瘤学家重点介绍这种罕见疾病。
一名19岁女性患者因月经不规律、多毛和腹围增加入院。体格检查发现双侧卵巢肿块、多毛和腹水。血清CA-125水平略有升高。术前MRI检查显示双侧低信号分叶状卵巢肿块。初步诊断为卵巢肿瘤后，我们进行了剖腹探查并切除了两个肿块。最终病理报告为双侧卵巢纤维瘤病。
卵巢纤维瘤病通常表现为腹水和盆腔实性肿块，可能被误诊为恶性卵巢肿瘤。在年轻患者中，临床医生在盆腔肿块的鉴别诊断中应考虑卵巢纤维瘤病。术前MRI表现和术中冰冻检查可用于避免不必要的积极手术治疗。
