卵巢细胞性纤维瘤伴梅格斯综合征及CA-125升高：一例报告

Cellular fibroma of the ovary with Meigs' syndrome and elevated CA-125. A case report.

作者信息

Siddiqui M, Toub D B

机构信息

Department of Medicine and Gynecology, Graduate Hospital, Philadelphia, Pennsylvania 19125, USA.

出版信息

J Reprod Med. 1995 Nov;40(11):817-9.

PMID:8592321

Abstract

BACKGROUND

Cellular fibroma of the ovary is an uncommon benign tumor. When associated with Meigs' syndrome, it can produce a clinical picture similar to that of ovarian carcinoma.

CASE

A 73-year-old nulligravida was admitted to the hospital with progressive cachexia, ascites, a right pleural effusion and a 15-cm pelvic mass. The serum CA-125 level was 1,780. Due to a high suspicion of ovarian carcinoma, the patient underwent exploratory laparotomy, total abdominal hysterectomy/bilateral salpingooophorectomy and surgical staging for a frozen section diagnosis of sarcoma. Permanent histology revealed the tumor to be a cellular fibroma, and the CA-125 levels fell to normal postoperatively.

CONCLUSION

Since benign ovarian tumors may mimic carcinoma, laparotomy and appropriate surgical staging are essential for the final diagnosis.

摘要

背景

卵巢细胞性纤维瘤是一种罕见的良性肿瘤。当与梅格斯综合征相关时，它可产生与卵巢癌相似的临床表现。

病例

一名73岁未孕女性因进行性恶病质、腹水、右侧胸腔积液及一个15厘米的盆腔肿块入院。血清CA - 125水平为1780。由于高度怀疑卵巢癌，患者接受了剖腹探查、全腹子宫切除术/双侧输卵管卵巢切除术及手术分期，以进行肉瘤的冰冻切片诊断。永久组织学检查显示肿瘤为细胞性纤维瘤，术后CA - 125水平降至正常。