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用PENELOPE测试的Leksell伽玛刀源通道简化模型。

A simplified model of the source channel of the Leksell GammaKnife tested with PENELOPE.

作者信息

Al-Dweri Feras M O, Lallena Antonio M, Vilches Manuel

机构信息

Departamento de Física Moderna, Universidad de Granada, E-18071 Granada, Spain.

出版信息

Phys Med Biol. 2004 Jun 21;49(12):2687-703. doi: 10.1088/0031-9155/49/12/015.

Abstract

Monte Carlo simulations using the code PENELOPE have been performed to test a simplified model of the source channel geometry of the Leksell GammaKnife. The characteristics of the radiation passing through the treatment helmets are analysed in detail. We have found that only primary particles emitted from the source with polar angles smaller than 3 degrees with respect to the beam axis are relevant for the dosimetry of the Gamma Knife. The photon trajectories reaching the output helmet collimators at (x, v, z = 236 mm) show strong correlations between rho = (x2 + y2)(1/2) and their polar angle theta, on one side, and between tan(-1)(y/x) and their azimuthal angle phi, on the other. This enables us to propose a simplified model which treats the full source channel as a mathematical collimator. This simplified model produces doses in good agreement with those found for the full geometry. In the region of maximal dose, the relative differences between both calculations are within 3%, for the 18 and 14 mm helmets, and 10%, for the 8 and 4 mm ones. Besides, the simplified model permits a strong reduction (larger than a factor 15) in the computational time.

摘要

已使用PENELOPE代码进行了蒙特卡罗模拟,以测试Leksell伽玛刀源通道几何结构的简化模型。详细分析了穿过治疗头盔的辐射特性。我们发现,只有相对于束轴极角小于3度的源发射的初级粒子与伽玛刀的剂量测定相关。到达输出头盔准直器(x,v,z = 236 mm)的光子轨迹一方面显示出ρ = (x² + y²)^(1/2) 与其极角θ之间有很强的相关性,另一方面显示出tan⁻¹(y/x) 与其方位角φ之间有很强的相关性。这使我们能够提出一个简化模型,将整个源通道视为一个数学准直器。这个简化模型产生的剂量与完整几何结构的剂量非常吻合。在最大剂量区域,对于18毫米和14毫米的头盔,两种计算之间的相对差异在3%以内,对于8毫米和4毫米的头盔,相对差异在10%以内。此外,简化模型可使计算时间大幅减少(大于15倍)。

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