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足月儿高胆红素血症的诊断与管理:为了更安全的第一周

Diagnosis and management of hyperbilirubinemia in the term neonate: for a safer first week.

作者信息

Bhutani Vinod K, Johnson Lois H, Keren Ron

机构信息

Department of Pediatrics, University of Pennsylvania School of Medicine, 800 Spruce Street, Philadelphia, PA 19107, USA.

出版信息

Pediatr Clin North Am. 2004 Aug;51(4):843-61, vii. doi: 10.1016/j.pcl.2004.03.011.

Abstract

New data support restructuring the approach toward diagnosis and management of hyperbilirubenia in the term neonate to make it more physician-friendly and gain wider implementation. The authors advocate clear criteria for patient safety, preventive approaches, and timely interventions. Structural changes to facilitate a system-based approach should include predischarge bilirubin management; follow-up bilirubin management; and lactational support and nutritional management. The authors advocate total serum bilirubin screening and a scoring system based on clinical risk factors as predischarge screening strategies; we should screen all babies for hyperbilirubinemia and for targeted follow-up based on an hour-specific total serum bilirubin measured for risk assessment. We should also provide focused universal education emphasizing adequate lactational nutrition, to decrease severe hyperbilirubinemia and thus prevent kernicterus.

摘要

新数据支持调整足月儿高胆红素血症的诊断和管理方法,使其对医生更友好并得到更广泛应用。作者主张制定明确的患者安全标准、预防方法和及时干预措施。为促进基于系统的方法而进行的结构调整应包括出院前胆红素管理、随访胆红素管理以及哺乳支持和营养管理。作者主张将总血清胆红素筛查和基于临床风险因素的评分系统作为出院前筛查策略;我们应该对所有婴儿进行高胆红素血症筛查,并根据为风险评估而测量的特定时间点的总血清胆红素进行有针对性的随访。我们还应提供重点突出的普及教育,强调充足的哺乳营养,以减少重度高胆红素血症,从而预防核黄疸。

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