子宫及宫颈广泛砂粒体样钙化伴子宫浆液性癌。
Extensive psammomatous calcification of the uterus and cervix associated with a uterine serous carcinoma.
作者信息
Cameron R I, McCluggage W G
机构信息
Department of Pathology, Royal Group of Hospitals Trust, Belfast BT12 6BL, Northern Ireland.
出版信息
J Clin Pathol. 2004 Aug;57(8):888-90. doi: 10.1136/jcp.2004.017004.
This report describes a uterine serous carcinoma with bilateral ovarian metastasis, which was associated with widespread extensive psammomatous calcification of the uterine leiomyomata, the myometrium, and the cervical stroma. These psammoma bodies were not associated with tumour or epithelial elements. This psammomatous calcification is rare, with no previous reports of similar cases. The presence of psammoma bodies is probably related to the serous carcinoma, raising the possibility that psammoma body formation in serous carcinomas is the result of a factor secreted locally by the tumour, rather than the widely held theory that their formation is secondary to necrosis, with subsequent dystrophic calcification within a papillary neoplasm.
本报告描述了一例伴有双侧卵巢转移的子宫浆液性癌，其与子宫平滑肌瘤、子宫肌层和宫颈间质广泛的砂粒体钙化相关。这些砂粒体与肿瘤或上皮成分无关。这种砂粒体钙化很罕见，此前没有类似病例的报道。砂粒体的存在可能与浆液性癌有关，这增加了浆液性癌中砂粒体形成是由肿瘤局部分泌的一种因子所致的可能性，而非广泛认为的其形成继发于坏死，随后在乳头状肿瘤内发生营养不良性钙化的理论。
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