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[一名失代偿期酒精性肝硬化患者的自发性细菌性腹膜炎]

[Spontaneous bacterial peritonitis in a patient with decompensated alcoholic cirrhosis of the liver].

作者信息

Nechwatal R, Lutz H

机构信息

I. Medizinische Klinik, Klinikum Bayreuth.

出版信息

Leber Magen Darm. 1992 Jul;22(4):156-9.

PMID:1528085
Abstract

Spontaneous bacterial peritonitis (SBP) constitute a rare complication of cirrhosis of the liver with a high mortality rate. Unspecific sings of decompensation like increasing elaboration of ascites or the development of hepatic encephalopathy are often prevailing. Fever and peripheral blood leukocytosis as well as abdominal sings of peritonitis are not rarely completely missing. There is a strong suspicion of SBP with an ascitic polymorphonuclear count of greater than 500/mm3. Determination of lactate and pH in the ascitic fluid can increase diagnostic sensitivity and specificity if the leukocyte count is dubious. Gram negative rods predominate with over 70% whereas anaerobic organisms appear to be very rare. A 49 year old patient is presented and diagnostic and therapeutic strategies reviewed. In view of the high mortality every clinical deterioration of patients with cirrhosis should alert the physician of the presence of SBP.

摘要

自发性细菌性腹膜炎(SBP)是肝硬化的一种罕见并发症,死亡率很高。失代偿的非特异性体征,如腹水生成增多或肝性脑病的发生,往往较为常见。发热、外周血白细胞增多以及腹膜炎的腹部体征常常完全缺失。腹水多形核细胞计数大于500/mm³时,强烈怀疑为SBP。如果白细胞计数不确定,测定腹水乳酸和pH值可提高诊断的敏感性和特异性。革兰氏阴性杆菌占比超过70%,而厌氧菌似乎非常罕见。本文介绍了一名49岁患者,并对诊断和治疗策略进行了回顾。鉴于高死亡率,肝硬化患者的每一次临床病情恶化都应提醒医生警惕SBP的存在。

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