Institut de Biologia Evolutiva (CSIC-UPF), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.
BIOMICs Research Group, Lascaray Research Center, University of the Basque Country UPV/EHU, Vitoria-Gasteiz, Spain.
Sci Rep. 2017 Aug 4;7(1):7341. doi: 10.1038/s41598-017-07710-x.
Haplogroup R1b-M269 comprises most Western European Y chromosomes; of its main branches, R1b-DF27 is by far the least known, and it appears to be highly prevalent only in Iberia. We have genotyped 1072 R1b-DF27 chromosomes for six additional SNPs and 17 Y-STRs in population samples from Spain, Portugal and France in order to further characterize this lineage and, in particular, to ascertain the time and place where it originated, as well as its subsequent dynamics. We found that R1b-DF27 is present in frequencies ~40% in Iberian populations and up to 70% in Basques, but it drops quickly to 6-20% in France. Overall, the age of R1b-DF27 is estimated at ~4,200 years ago, at the transition between the Neolithic and the Bronze Age, when the Y chromosome landscape of W Europe was thoroughly remodeled. In spite of its high frequency in Basques, Y-STR internal diversity of R1b-DF27 is lower there, and results in more recent age estimates; NE Iberia is the most likely place of origin of DF27. Subhaplogroup frequencies within R1b-DF27 are geographically structured, and show domains that are reminiscent of the pre-Roman Celtic/Iberian division, or of the medieval Christian kingdoms.
单倍群 R1b-M269 包含了大多数西欧的 Y 染色体；在其主要分支中，R1b-DF27 是目前所知最少的，而且似乎只在伊比利亚半岛高度流行。我们对来自西班牙、葡萄牙和法国的人群样本中的 1072 条 R1b-DF27 染色体进行了六个额外 SNP 和 17 个 Y-STR 的基因分型，以进一步描述这一谱系，特别是确定它起源的时间和地点，以及其后的动态。我们发现，R1b-DF27 在伊比利亚人群中的频率约为 40%，在巴斯克人中高达 70%，但在法国迅速降至 6-20%。总体而言，R1b-DF27 的年龄估计约为 4200 年前，处于新石器时代和青铜时代之交，当时 W 欧洲的 Y 染色体景观被彻底重塑。尽管在巴斯克人中 R1b-DF27 的频率很高，但那里的 R1b-DF27 的 Y-STR 内部多样性较低，导致年龄估计更接近现代；伊比利亚东北部最有可能是 DF27 的起源地。R1b-DF27 内的亚单倍群频率在地理上是有结构的，显示出类似于前罗马凯尔特/伊比利亚分裂或中世纪基督教王国的区域。
