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温石棉作为间皮瘤的病因:希尔因果关系模型的应用。

Chrysotile asbestos as a cause of mesothelioma: application of the Hill causation model.

作者信息

Lemen Richard A

出版信息

Int J Occup Environ Health. 2004 Apr-Jun;10(2):233-9. doi: 10.1179/oeh.2004.10.2.233.

Abstract

Chrysotile comprises over 95% of the asbestos used today. Some have contended that the majority of asbestos-related diseases have resulted from exposures to the amphiboles. In fact, chrysotile is being touted as the form of asbestos which can be used safely. Causation is a controversial issue for the epidemiologist. How much proof is needed before causation can be established? This paper examines one proposed model for establishing causation as presented by Sir Austin Bradford Hill in 1965. Many policymakers have relied upon this model in forming public health policy as well as deciding litigation issues. Chrysotile asbestos meets Hill's nine proposed criteria, establishing chrysotile asbestos as a cause of mesothelioma.

摘要

温石棉占当今使用的石棉的95%以上。一些人认为,大多数与石棉相关的疾病是由接触闪石引起的。事实上,温石棉被吹捧为可以安全使用的石棉形式。因果关系对流行病学家来说是一个有争议的问题。在确定因果关系之前需要多少证据?本文考察了奥斯汀·布拉德福德·希尔爵士在1965年提出的一种确定因果关系的模型。许多政策制定者在制定公共卫生政策以及决定诉讼问题时都依赖于这个模型。温石棉符合希尔提出的九条标准,从而确定温石棉是间皮瘤的一个病因。

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