Coccaro Emil F, Schmidt Catherine A, Samuels Jack F, Nestadt Gerald
Clinical Neuroscience and Psychopharmacology Research Unit, Department of Psychiatry, The Pritzker School of Medicine, University of Chicago, IL 60637, USA.
J Clin Psychiatry. 2004 Jun;65(6):820-4. doi: 10.4088/jcp.v65n0613.
To determine the lifetime and 1-month prevalence of intermittent explosive disorder (IED) by both DSM-IV and research criteria in a community sample.
The final 253 (34.1%) of individuals who were entered into the Hopkins Epidemiology Study of Personality Disorder and sampled in the context of a follow-up study of participants from the Baltimore Epidemiologic Catchment Area (ECA) study completed a supplemental interview that allowed for the determination of IED by DSM-IV and/or research criteria.
The mean +/- SE percentage of subjects who met inclusion criteria was 11.07% +/- 1.97%, and 6.32% +/- 1.53% met full criteria, for lifetime IED by either diagnostic criteria set; 2.37% +/- 0.96% met full criteria for IED within the previous 1 month. Adjusting the prevalence rates to account for differential sampling from the original ECA study did not substantially affect these results. Onset of problematic aggressive behavior in IED subjects (described as lifelong in most subjects) began as early as childhood, peaked in the third decade, and declined steadily after the fifth decade. While distress and/or impairment due to aggressive behavior was documented in 87.5% of IED subjects, only 12.5% of IED subjects reported seeking help for this problem.
Intermittent problematic aggressive behavior in the community, as defined by IED, may be far more common than previously thought. Conservatively estimated, the number of individuals in the United States with IED, based on these data, may be no lower than 1.4 million for current IED or nearly 10 million for lifetime IED.
通过DSM-IV和研究标准确定社区样本中间歇性爆发障碍(IED)的终生患病率和1个月患病率。
参与巴尔的摩流行病学集水区(ECA)研究的参与者进行随访研究时,进入霍普金斯人格障碍流行病学研究的最终253名个体(占34.1%)完成了一项补充访谈,该访谈可根据DSM-IV和/或研究标准确定IED。
符合纳入标准的受试者的平均±标准误百分比为11.07%±1.97%,根据任一诊断标准集,终生IED的完全符合标准者为6.32%±1.53%;在过去1个月内,2.37%±0.96%的人完全符合IED标准。调整患病率以考虑与原始ECA研究的差异抽样,对这些结果没有实质性影响。IED受试者中有问题的攻击性行为的发作(大多数受试者描述为终生存在)最早始于童年,在第三个十年达到高峰,在第五个十年后稳步下降。虽然87.5%的IED受试者记录了攻击性行为导致的痛苦和/或损害,但只有12.5%的IED受试者报告为此问题寻求过帮助。
由IED定义的社区中间歇性有问题的攻击性行为可能比以前认为的更为常见。根据这些数据保守估计,美国目前患有IED的人数可能不低于140万,终生患有IED的人数可能接近1000万。