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Haploview:连锁不平衡(LD)和单倍型图谱的分析与可视化

Haploview: analysis and visualization of LD and haplotype maps.

作者信息

Barrett J C, Fry B, Maller J, Daly M J

机构信息

Whitehead Institute for Biomedical Research Cambridge, MA 02142, USA.

出版信息

Bioinformatics. 2005 Jan 15;21(2):263-5. doi: 10.1093/bioinformatics/bth457. Epub 2004 Aug 5.

Abstract

UNLABELLED

Research over the last few years has revealed significant haplotype structure in the human genome. The characterization of these patterns, particularly in the context of medical genetic association studies, is becoming a routine research activity. Haploview is a software package that provides computation of linkage disequilibrium statistics and population haplotype patterns from primary genotype data in a visually appealing and interactive interface.

AVAILABILITY

http://www.broad.mit.edu/mpg/haploview/

CONTACT

jcbarret@broad.mit.edu

摘要

未标注

过去几年的研究揭示了人类基因组中显著的单倍型结构。对这些模式的表征,特别是在医学遗传关联研究的背景下,正成为一项常规研究活动。Haploview是一个软件包,它通过一个视觉上吸引人且交互式的界面,从原始基因型数据计算连锁不平衡统计量和群体单倍型模式。

可用性

http://www.broad.mit.edu/mpg/haploview/

联系方式

jcbarret@broad.mit.edu

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