Barrett J C, Fry B, Maller J, Daly M J
Whitehead Institute for Biomedical Research Cambridge, MA 02142, USA.
Bioinformatics. 2005 Jan 15;21(2):263-5. doi: 10.1093/bioinformatics/bth457. Epub 2004 Aug 5.
Research over the last few years has revealed significant haplotype structure in the human genome. The characterization of these patterns, particularly in the context of medical genetic association studies, is becoming a routine research activity. Haploview is a software package that provides computation of linkage disequilibrium statistics and population haplotype patterns from primary genotype data in a visually appealing and interactive interface.
http://www.broad.mit.edu/mpg/haploview/
过去几年的研究揭示了人类基因组中显著的单倍型结构。对这些模式的表征,特别是在医学遗传关联研究的背景下,正成为一项常规研究活动。Haploview是一个软件包,它通过一个视觉上吸引人且交互式的界面,从原始基因型数据计算连锁不平衡统计量和群体单倍型模式。
http://www.broad.mit.edu/mpg/haploview/