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立陶宛类风湿关节炎和脊柱关节炎患病率调查

Prevalence survey of rheumatoid arthritis and spondyloarthropathy in Lithuania.

作者信息

Adomaviciute D, Pileckyte M, Baranauskaite A, Morvan J, Dadoniene J, Guillemin F

机构信息

Institute of Experimental and Clinical Medicine at Vilnius University, Vilnius, Lithuania.

出版信息

Scand J Rheumatol. 2008 Mar-Apr;37(2):113-9. doi: 10.1080/03009740701774966.

Abstract

OBJECTIVE

To assess the prevalence of rheumatoid arthritis (RA) and spondyloarthropathy (SpA) in two Lithuanian cities, Vilnius and Kaunas.

METHODS

The first step in this study involved the translation and validation of a telephone questionnaire developed by rheumatologists and epidemiologists in France. The second step comprised the prevalence survey. To detect RA and SpA cases in the populations of Vilnius and Kaunas, 6542 subjects selected randomly (every 50th) from the latest telephone book were interviewed by telephone using a validated case detection questionnaire (the screening phase). All subjects with rheumatic symptoms but an uncertain diagnosis were contacted by a rheumatologist (confirmation phase) by telephone. If the diagnosis remained uncertain, the subjects were invited for a rheumatological examination.

RESULTS

We attempted to contact 3370 telephone numbers in Vilnius and 3172 in Kaunas, and had a response rate of 62.5% and 67.7%, respectively. Over the course of all the study phases (telephone interview, rheumatologist's interview, and clinical examination), 39 RA cases and 27 SpA cases were detected, resulting in a crude prevalence of 0.92% for RA (95% CI 0.65-1.25) and 0.64% (95% CI 0.42-0.92) for SpA. The standardized prevalence rate according to age and sex in the Lithuanian population showed an RA prevalence of 0.55 (95% CI 0.39-0.74) and a SpA prevalence of 0.84 (95% CI 0.53-1.21).

CONCLUSIONS

The prevalence of RA and SpA in Lithuania was found to be one of the higher rates in Europe. A telephone interview using a validated short questionnaire enabled a cost- and time-saving epidemiological survey to be conducted to detect RA and SpA cases in the community.

摘要

目的

评估立陶宛的维尔纽斯和考纳斯这两个城市中类风湿关节炎(RA)和脊柱关节炎(SpA)的患病率。

方法

本研究的第一步是对法国风湿病学家和流行病学家编制的电话调查问卷进行翻译和验证。第二步是患病率调查。为了在维尔纽斯和考纳斯的人群中检测RA和SpA病例,从最新电话簿中随机抽取(每第50个)6542名受试者,使用经过验证的病例检测问卷通过电话进行访谈(筛查阶段)。所有有风湿症状但诊断不明确的受试者由风湿病学家通过电话联系(确认阶段)。如果诊断仍不明确,则邀请受试者进行风湿病检查。

结果

我们试图联系维尔纽斯的3370个电话号码和考纳斯的3172个电话号码,并分别获得了62.5%和67.7%的回复率。在所有研究阶段(电话访谈、风湿病学家访谈和临床检查)中,共检测到39例RA病例和27例SpA病例,RA的粗患病率为0.92%(95%可信区间0.65 - 1.25),SpA为0.64%(95%可信区间0.42 - 0.92)。根据立陶宛人口年龄和性别标准化后的患病率显示,RA患病率为0.55(95%可信区间0.39 - 0.74),SpA患病率为0.84(95%可信区间0.53 - 1.21)。

结论

立陶宛的RA和SpA患病率在欧洲处于较高水平之一。使用经过验证的简短问卷进行电话访谈能够开展一项节省成本和时间的流行病学调查,以在社区中检测RA和SpA病例。

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