Birlik M, Gurler O, Akar S, Sari I, Onen F, Akkoc N
Division of Immunology-Rheumatology, Department of Internal Medicine, Dokuz Eylul University School of Medicine, Izmir, Turkey.
Int J Clin Pract. 2014 Jun;68(6):775-82. doi: 10.1111/ijcp.12377. Epub 2014 Feb 18.
This study aimed to determine the prevalence of gout in a general Turkish population, according to the American College of Rheumatology (Wallace) criteria proposed for gout classification.
This study was conducted in two districts of Izmir Province in Turkey, and involved 2835 subjects of ≥ 20 years of age. In the first stage, face-to-face interviews were performed at the subjects' registered households. In the second stage, subjects who gave positive answers in the screening questionnaire were invited to the hospital for a full examination, which included a detailed medical history, medication use and blood tests.
A total of 2887 subjects were contacted, and complete interviews were obtained for 2835 (1551 women, 1284 men). A total of 312 subjects (227 women, 85 men) reported experiencing a short period of joint pain accompanied by swelling, redness or reduced range of movement, and 247 (79%) of these patients underwent a detailed clinical examination in the hospital. Gout was diagnosed in 11 patients (8 men, 3 women). We found minimum age- and sex-adjusted prevalence rates of gout of 0.31% (95% CI: 0.16-0.61) in subjects of ≥ 20 years of age, and 0.72% (95% CI: 0.37-1.24) in subjects of ≥ 40 years of age.
Our data suggest that the estimated prevalence of gout (0.31%) is lower than the previously published estimated prevalence of rheumatoid arthritis (0.36%) in the same study population (14 definite rheumatoid arthritis cases among the 2835 subjects).
本研究旨在根据美国风湿病学会（华莱士）提出的痛风分类标准，确定土耳其普通人群中痛风的患病率。
本研究在土耳其伊兹密尔省的两个区进行，纳入了2835名年龄≥20岁的受试者。第一阶段，在受试者登记的家庭中进行面对面访谈。第二阶段，邀请在筛查问卷中给出肯定回答的受试者到医院进行全面检查，包括详细的病史、用药情况和血液检查。
共联系了2887名受试者，获得了2835名受试者（1551名女性，1284名男性）的完整访谈。共有312名受试者（227名女性，85名男性）报告经历过短时间的关节疼痛，并伴有肿胀、发红或活动范围减小，其中247名（79%）患者在医院接受了详细的临床检查。诊断出痛风患者11例（8名男性，3名女性）。我们发现，年龄和性别调整后的痛风患病率在≥20岁的受试者中为0.31%（95%CI：0.16 - 0.61），在≥40岁的受试者中为0.72%（95%CI：0.37 - 1.24）。
我们的数据表明，痛风的估计患病率（0.31%）低于同一研究人群中先前公布的类风湿关节炎估计患病率（0.36%）（2835名受试者中有14例确诊类风湿关节炎病例）。
