Kozel Frank Andrew, Padgett Tamara M, George Mark S
Center for Advanced Imaging Research and the Brain Stimulation Laboratory, Department of Psychiatry, Medical University of South Carolina, Charleston, SC 29425, USA.
Behav Neurosci. 2004 Aug;118(4):852-6. doi: 10.1037/0735-7044.118.4.852.
The authors attempted to replicate prior group brain correlates of deception and improve on the consistency of individual results. Healthy, right-handed adults were instructed to tell the truth or to lie while being imaged in a 3T magnetic resonance imaging (MRI) scanner. Blood oxygen level-dependent functional MRI significance maps were generated for subjects giving a deceptive answer minus a truthful answer (lie minus true) and the reverse (true minus lie). The lie minus true group analysis (n = 10) revealed significant activation in 5 regions, consistent with a previous study (right orbitofrontal, inferior frontal, middle frontal cortex, cingulate gyrus, and left middle frontal), with no significant activation for true minus lie. Individual results of the lie minus true condition were variable. Results show that functional MRI is a reasonable tool with which to study deception.
作者试图复制先前关于欺骗的大脑相关研究结果,并提高个体结果的一致性。健康的右利手成年人在3T磁共振成像(MRI)扫描仪中成像时,被指示说实话或说谎。为给出欺骗性答案减去真实答案(说谎减去真实)以及相反情况(真实减去说谎)的受试者生成了基于血氧水平依赖的功能MRI显著性图谱。说谎减去真实的组分析(n = 10)显示在5个区域有显著激活,与先前的一项研究一致(右侧眶额、额下回、额中回、扣带回和左侧额中回),而真实减去说谎则无显著激活。说谎减去真实条件下的个体结果存在差异。结果表明,功能MRI是研究欺骗的一种合理工具。