Wu Chuntao, Hannan Edward L, Ryan Thomas J, Bennett Edward, Culliford Alfred T, Gold Jeffrey P, Isom O Wayne, Jones Robert H, McNeil Barbara, Rose Eric A, Subramanian Valavanur A
University at Albany, State University of New York, One University Place, Rensselaer, NY 12144-3456, USA.
Circulation. 2004 Aug 17;110(7):784-9. doi: 10.1161/01.CIR.0000138744.13516.B5. Epub 2004 Aug 9.
Restriction of volume-based referral for CABG surgery to high-risk patients has been suggested, and earlier studies have reached different conclusions regarding volume-based referral for low-risk patients.
Patients who underwent isolated CABG surgery in New York from 1997 through 1999 (n=57 150) were separated into low-risk and moderate-to-high-risk groups with a predicted probability of in-hospital death of 2% as the cutoff point. The provider volume-mortality relationship was examined for both groups. For annual hospital volume thresholds between 200 and 600 cases, the adjusted ORs of in-hospital mortality for high-volume to low-volume hospitals ranged from 0.45 to 0.77 and were all significant for the low-risk group; for the moderate-to-high-risk group, ORs ranged from 0.62 to 0.91, and most were significant. The number needed to treat at higher-volume hospitals to avoid 1 death was greater for the low-risk group (a range of 114 to 446 versus 37 to 184). As the annual surgeon volume threshold increased from 50 to 150 cases, the ORs for high- to low-volume surgeons increased from 0.43 to 0.74 for the low-risk group; for the moderate-to-high-risk group, ORs ranged from 0.79 to 0.86. Compared with patients treated by surgeons with volumes of <125 in hospitals with volumes of <600, patients treated by higher-volume surgeons in higher-volume hospitals had a significantly lower risk of death; in particular, the OR was 0.52 for the low-risk group.
For both low-risk and moderate-to-high-risk patients, higher provider volume is associated with lower risk of death.
有人建议将基于手术量的冠状动脉旁路移植术(CABG)转诊限制在高危患者中,而早期研究对于低危患者基于手术量的转诊得出了不同结论。
1997年至1999年在纽约接受单纯CABG手术的患者(n = 57150)被分为低危组和中高危组,以预测的院内死亡概率2%作为分界点。对两组的医疗服务提供者手术量与死亡率的关系进行了研究。对于年手术量阈值在200至600例之间,高手术量医院与低手术量医院相比,低危组的院内死亡校正比值比(OR)范围为0.45至0.77,且均具有显著性;中高危组的OR范围为0.62至0.91,多数具有显著性。低危组在高手术量医院避免1例死亡所需治疗的患者数量更多(范围为114至446例,而中高危组为37至184例)。当年外科医生手术量阈值从50例增加到150例时,低危组高手术量与低手术量外科医生的OR从0.43增加到0.74;中高危组的OR范围为0.79至0.86。与在手术量<600例的医院中由手术量<125例的外科医生治疗的患者相比,在高手术量医院中由高手术量外科医生治疗的患者死亡风险显著更低;特别是,低危组的OR为0.52。
对于低危和中高危患者,更高的医疗服务提供者手术量与更低的死亡风险相关。