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补充经椎板小关节螺钉固定对生理压缩预负荷下单节段前路腰椎椎间融合器稳定性的影响。

Effect of supplemental translaminar facet screw fixation on the stability of stand-alone anterior lumbar interbody fusion cages under physiologic compressive preloads.

作者信息

Phillips Frank M, Cunningham Ben, Carandang Gerard, Ghanayem Alexander J, Voronov Leonard, Havey Robert M, Patwardhan Avinash G

机构信息

Department of Orthopaedic Surgery, Rush Presbyterian-St. Luke's Medical Center, Chicago, Illinois, USA.

出版信息

Spine (Phila Pa 1976). 2004 Aug 15;29(16):1731-6. doi: 10.1097/01.brs.0000134570.08901.30.

Abstract

STUDY DESIGN

A biomechanical study of lumbar threaded interbody cage construct under varying compressive preloads of similar magnitudes to those experienced in vivo during daily activities.

OBJECTIVES

To test the hypothesis that supplemental translaminar facet screws would enhance the stability (ability to reduce segmental angular motion) of threaded interbody cages in flexion-extension during activities in which the spine is subjected to low compressive preloads, and therefore the stand-alone interbody cage construct is least stable.

SUMMARY OF BACKGROUND DATA

Controversy exists over whether threaded anteriorly placed interbody cages can be routinely used as "stand-alone" devices or whether they require supplemental posterior stabilization to achieve successful fusion. Biomechanical studies suggest that under conditions of low preloads, the motion segment treated with stand-alone cages might be less stable, particularly in extension. METHODS.: Eight human lumbar spine specimens (from L1 to sacrum) were tested intact, after insertion of 2 threaded cylindrical cages (BAK) at L5-S1 and after supplemental translaminar facet screw fixation. They were subjected to flexion and extension moments under progressively increasing magnitude of externally applied compressive follower preload from 0 to 1200 N. The range of angular motion in flexion-extension at L5-S1 was analyzed to assess the effect of translaminar facet screws on the stability of the cage construct for different compressive preloads.

RESULTS

In flexion, over 0 to 400 N preload, the supplemental translaminar facet screw fixation reduced the L5-S1 angular motion relative to intact by 71% to 74% as compared to 40% to 44% for the cages alone. This difference was statistically significant (P < 0.05). In extension at 0 N preload, the cages allowed more angular motion than the intact segment, whereas with translaminar facet screw fixation, the motion was reduced to the level of the intact segment. At 400 N preload, supplemental TLFS fixation significantly increased the stability of the cages, reducing the extension angular motion by 60% of intact (P = 0.04). Supplemental translaminar facet screw fixation did not significantly increase the stability provided by the cages in flexion or extension at the 1200 N preload magnitude.

CONCLUSIONS

In vivo during activities of daily living, interbody cage constructs are subject to varying compressive preloads due to external loads generated by paraspinal musculature, and our results suggest that the stability created by the cage (reduction in segmental angular motion) is not constant. The cage construct is likely to be least stable in extension during activities that impart low compressive preloads to the lumbar spine. Supplemental translaminar facet screw fixation will enhance stability of the motion segment treated with threaded cages, particularly during conditions of low compressive preloads, the very condition in which the cage alone is least effective in providing stability.

摘要

研究设计

对腰椎螺纹椎间融合器结构进行生物力学研究,施加的压缩预载荷大小与日常活动中体内所经历的相似。

目的

检验以下假设,即在脊柱承受低压缩预载荷(因此单独的椎间融合器结构最不稳定)的活动中,补充经椎板小关节螺钉可增强螺纹椎间融合器在屈伸时的稳定性(减少节段角运动的能力)。

背景资料总结

对于前路放置的螺纹椎间融合器是否可常规用作“单独”装置,或者它们是否需要补充后路稳定以实现成功融合,存在争议。生物力学研究表明,在低预载荷条件下,用单独融合器治疗的运动节段可能稳定性较差,尤其是在伸展时。方法:对8个完整的人腰椎标本(从L1到骶骨)进行测试,在L5 - S1处插入2个螺纹圆柱形融合器(BAK)后以及补充经椎板小关节螺钉固定后进行测试。它们在从0到1200 N逐渐增加的外部施加的压缩跟随预载荷下承受屈伸力矩。分析L5 - S1在屈伸时的角运动范围,以评估经椎板小关节螺钉对不同压缩预载荷下融合器结构稳定性的影响。

结果

在屈曲时,在0至400 N预载荷范围内,补充经椎板小关节螺钉固定使L5 - S1相对于完整状态的角运动减少了71%至74%,而单独使用融合器时为40%至44%。这种差异具有统计学意义(P < 0.05)。在0 N预载荷下伸展时,融合器允许的角运动比完整节段更多,而采用经椎板小关节螺钉固定时,运动减少到完整节段的水平。在400 N预载荷下,补充经椎板小关节螺钉固定显著增加了融合器的稳定性,使伸展角运动减少了完整状态的60%(P = 0.04)。在1200 N预载荷时,补充经椎板小关节螺钉固定在屈曲或伸展时并未显著增加融合器提供的稳定性。

结论

在日常生活活动中,由于椎旁肌肉组织产生的外部载荷,椎间融合器结构会受到不同的压缩预载荷,我们的结果表明融合器产生的稳定性(节段角运动的减少)并非恒定。在给腰椎施加低压缩预载荷的活动中,融合器结构在伸展时可能最不稳定。补充经椎板小关节螺钉固定将增强用螺纹融合器治疗的运动节段的稳定性,特别是在低压缩预载荷条件下,而单独使用融合器在这种条件下提供稳定性的效果最差。

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