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山梨醇不仅可以通过化学方法生产,也可以通过生物技术方法生产。

Sorbitol can be produced not only chemically but also biotechnologically.

作者信息

Jonas Rainer, Silveira Mauricio M

机构信息

Gesellschaft für Biotechnologische Forschung mbh., Mascheroder Weg 1, D-38124 Braunschweig, Germany.

出版信息

Appl Biochem Biotechnol. 2004 Jul-Sep;118(1-3):321-36. doi: 10.1385/abab:118:1-3:321.

Abstract

Sorbitol, a polyol found in many fruits, is attracting increasing industrial interest as a sweetener, humectant, texturizer, and softener. It is principally produced by chemical means. The bacterium Zymomonas mobilis is able to produce sorbitol together with gluconic acid from fructose and glucose, respectively. This is possible in a one-step reaction via the enzyme glucose-fructose oxidoreductase, so far only known from Z. mobilis. The possibilities for the production of sorbitol by Z. mobilis are discussed also under the aspect of an industrial process and compared with the current chemical as well as other microbiologic processes. The production process by Z. mobilis shows economic possibilities for certain countries, such as Brazil, considering only the products sorbitol and ethanol as an important byproduct. For the other byproduct, gluconic acid, further studies for its partial substitution must be conducted.

摘要

山梨醇是一种存在于多种水果中的多元醇,作为甜味剂、保湿剂、增稠剂和软化剂,正吸引着越来越多的工业关注。它主要通过化学方法生产。运动发酵单胞菌能够分别从果糖和葡萄糖中产生山梨醇和葡萄糖酸。这可以通过葡萄糖 - 果糖氧化还原酶在一步反应中实现,到目前为止,这种酶仅在运动发酵单胞菌中发现。还从工业生产过程的角度讨论了运动发酵单胞菌生产山梨醇的可能性,并与当前的化学方法以及其他微生物方法进行了比较。仅考虑山梨醇产品和作为重要副产品的乙醇,运动发酵单胞菌的生产过程对某些国家(如巴西)显示出经济潜力。对于另一种副产品葡萄糖酸,必须对其部分替代进行进一步研究。

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