Holtedahl Robin
Tidsskr Nor Laegeforen. 2004 Aug 12;124(15):1930-2.
Chronic musculoskeletal complaints are common in the clinical setting and a therapeutic challenge. Little is known about the extent and type of pain-relieving drugs used by these patients in Norway.
500 patients were referred for specialist evaluation because of chronic musculoskeletal pain, most of them from the National Insurance Administration. The diagnoses were grouped into four main categories. 95% of the patients had non-specific myofascial pain syndromes and about 5% had some form of osteoarthritis. In the majority the pain was chronic. All patients were asked which pain-relieving drugs they had taken during the previous week, prescribed drugs as well as over-the-counter drugs. Those taking non-steroidal anti-inflammatory drugs (NSAIDs) were also asked if these had been prescribed under the National Health Insurance scheme.
40% had completely abstained from analgesics. 32% had taken an NSAID; 20% a codeine-paracetamol compound; 15% paracetamol; 8% muscle-relaxants, while 26 patients had taken some other type of medication. About two thirds of the patients reported having received reimbursable NSAID-prescriptions, of which only about 9% were judged to qualify for this.
Even though a substantial number of patients had not taken pain-relieving drugs during the previous week, the number of patients having taken either NSAIDs, opioids or muscle relaxants was relatively high, both with regard to actual or potential side effects and to existing recommendations. The study also suggests that stricter application of the rules for reimbursement of drugs seems justified.
慢性肌肉骨骼疾病在临床环境中很常见,是一个治疗难题。对于挪威这些患者使用的止痛药物的范围和类型,人们了解甚少。
500名因慢性肌肉骨骼疼痛而被转诊进行专科评估的患者,其中大多数来自国家保险管理局。诊断分为四大类。95%的患者患有非特异性肌筋膜疼痛综合征,约5%患有某种形式的骨关节炎。大多数患者的疼痛是慢性的。所有患者都被问及他们在前一周服用了哪些止痛药物,包括处方药和非处方药。服用非甾体抗炎药(NSAIDs)的患者还被问及这些药物是否是根据国家健康保险计划开具的。
40%的患者完全没有服用止痛药。32%的患者服用了非甾体抗炎药;20%的患者服用了可待因 - 对乙酰氨基酚复方制剂;15%的患者服用了对乙酰氨基酚;8%的患者服用了肌肉松弛剂,而26名患者服用了其他类型的药物。约三分之二的患者报告收到了可报销的非甾体抗炎药处方,其中只有约9%被认为符合报销条件。
尽管相当数量的患者在前一周没有服用止痛药物,但服用非甾体抗炎药、阿片类药物或肌肉松弛剂的患者数量相对较高,无论是从实际或潜在的副作用还是现有建议来看。该研究还表明,更严格地应用药物报销规则似乎是合理的。