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利奈唑胺治疗万古霉素中介金黄色葡萄球菌心内膜炎

Treatment of vancomycin-intermediate Staphylcoccus aureus endocarditis with linezolid.

作者信息

Leung K T, Tong M K H, Siu Y P, Lam C S, Ng H L, Lee H K

机构信息

Department of Medicine, Tuen Mun Hospital, Tuen Mun, Hong Kong, China.

出版信息

Scand J Infect Dis. 2004;36(6-7):483-5. doi: 10.1080/00365540410015907.

Abstract

We report a case of infective endocarditis due to vancomycin-intermediate Staphylococcus aureus that developed after repeated courses of vancomycin. The patient had underlying end stage renal disease and dissecting aortic aneurysm with aortic graft and prosthetic aortic valve replacement. He responded to prolonged combination therapy with linezolid and amikacin without undergoing surgical intervention.

摘要

我们报告一例由万古霉素中介金黄色葡萄球菌引起的感染性心内膜炎,该病例在多次使用万古霉素疗程后发生。患者有终末期肾病基础,合并主动脉夹层动脉瘤并接受了主动脉移植及人工主动脉瓣置换术。他在未接受手术干预的情况下,通过长期联合使用利奈唑胺和阿米卡星治疗取得了疗效。

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