Chiang Fu-Yu, Climo Michael
Division of Infectious Disease, Virginia Commonwealth University Health Systemthe, Richmond, Virginia, USA.
Antimicrob Agents Chemother. 2003 Sep;47(9):3002-4. doi: 10.1128/AAC.47.9.3002-3004.2003.
The levels of effectiveness of linezolid, vancomycin, and the combination of linezolid and vancomycin were compared in the rabbit model of endocarditis caused by a clinical methicillin-resistant Staphylococcus aureus (MRSA) isolate. Vancomycin alone was more effective than either linezolid alone or the combination of linezolid and vancomycin for the treatment of endocarditis due to MRSA.
在由临床耐甲氧西林金黄色葡萄球菌(MRSA)分离株引起的心内膜炎兔模型中,比较了利奈唑胺、万古霉素以及利奈唑胺与万古霉素联合用药的有效性水平。单独使用万古霉素在治疗由MRSA引起的心内膜炎方面比单独使用利奈唑胺或利奈唑胺与万古霉素联合用药更有效。