Nam Hae-Seon, Park Choon-Sik, Crane Julian, Siebers Rob
Genome Research Center for Allergy and Respiratory Diseases, Soonchunhyang University, Bucheon, Korea.
J Korean Med Sci. 2004 Aug;19(4):505-8. doi: 10.3346/jkms.2004.19.4.505.
Pillows are known to contain significant levels of indoor allergens and endotoxin, that are of importance to house dust mite sensitized asthmatics. Buckwheat pillows are commonly used in Korea. We studied the levels of the house dust mite allergen, Der f 1, and endotoxin on new synthetic and buckwheat pillows and their accumulation over three months. Endotoxin levels were significantly higher on new buckwheat pillows compared to synthetic pillows; geometric mean levels (95% CI) were 60,950 EU/g (30,270-122,700) and 4,887 EU/g (2,570-9,311) respectively (p<0.001). No Der f 1 was detected on the new pillows. After three months Der f 1 levels were similar on buckwheat and synthetic pillows, geometric mean levels (95% CI) were 1.16 microg/g (0.02-8.13) and 1.08 microg/g (0.19-1.68) respectively. These results indicate that buckwheat pillows are a source of very high endotoxin levels that may be of relevance to asthma severity of atopic asthmatics.
众所周知,枕头含有大量室内过敏原和内毒素,这对尘螨致敏哮喘患者很重要。荞麦枕头在韩国很常用。我们研究了新的合成枕头和荞麦枕头上屋尘螨过敏原Der f 1和内毒素的水平及其在三个月内的积累情况。新荞麦枕头上的内毒素水平显著高于合成枕头;几何平均水平(95%置信区间)分别为60,950 EU/g(30,270 - 122,700)和4,887 EU/g(2,570 - 9,311)(p<0.001)。新枕头上未检测到Der f 1。三个月后,荞麦枕头和合成枕头上的Der f 1水平相似,几何平均水平(95%置信区间)分别为1.16微克/克(0.02 - 8.13)和1.08微克/克(0.19 - 1.68)。这些结果表明,荞麦枕头是内毒素水平非常高的一个来源,这可能与特应性哮喘患者的哮喘严重程度有关。