Fukamachi Kiyotaka
Department of Biomedical Engineering, Lerner Research Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
J Artif Organs. 2004;7(2):45-57. doi: 10.1007/s10047-004-0256-x.
Congestive heart failure remains a leading cause of morbidity and mortality in the United States, and alternatives to heart transplantation are urgently required. Mechanical circulatory support by ventricular assist devices and total artificial hearts have the potential to provide an alternative to heart transplantation if a small, durable, biocompatible, and totally implantable system is available. In this article, current technologies for mechanical circulatory support by implantable devices are reviewed and the current status and future prospects of the CorAide and MagScrew technologies, which have been developed and tested at the Cleveland Clinic Foundation, are presented.
在美国,充血性心力衰竭仍然是发病和死亡的主要原因,因此迫切需要心脏移植的替代方案。如果能有一个小型、耐用、生物相容性好且完全可植入的系统,那么通过心室辅助装置和全人工心脏进行机械循环支持有可能成为心脏移植的替代方案。本文回顾了目前可植入装置进行机械循环支持的技术,并介绍了在克利夫兰诊所基金会开发和测试的CorAide和MagScrew技术的现状和未来前景。