全人工心脏的现状

Current status of the total artificial heart.

作者信息

Gray Norman A, Selzman Craig H

机构信息

Division of Cardiothoracic Surgery, Department of Surgery, University of North Carolina, Chapel Hill, NC 27599, USA.

出版信息

Am Heart J. 2006 Jul;152(1):4-10. doi: 10.1016/j.ahj.2005.10.024.

DOI:10.1016/j.ahj.2005.10.024

PMID:16824826

Abstract

Although heart transplantation remains the gold standard for patients who remain in advanced heart failure despite optimal medical therapy, limited donor supplies allows for just >2000 transplant each year in the United States. Recent enthusiasm has developed for the role of mechanical circulatory support for this ever-growing population of sick patients. Although much attention has been directed toward ventricular assist devices, less information is available regarding the role of the total artificial heart. Indeed, efforts in this latter technology have allowed the relatively recent deployment of a variety of complete circulatory assist devices. The purpose of this article is to review the historical development, current use, and future role of total artificial hearts.

摘要

尽管心脏移植仍是那些尽管接受了最佳药物治疗但仍处于晚期心力衰竭患者的金标准，但供体供应有限，导致美国每年仅能进行2000多例移植手术。对于机械循环支持在这类不断增加的患病患者群体中的作用，近来人们的热情高涨。尽管很多注意力都集中在心室辅助装置上，但关于全人工心脏的作用的信息却较少。事实上，这项后一种技术的努力使得各种完整的循环辅助装置得以相对近期地部署。本文的目的是回顾全人工心脏的历史发展、当前应用及未来作用。