对一名克罗恩病患者回肠末端派尔集合淋巴结的内镜识别。
Endoscopic identification of Peyer's patches of the terminal ileum in a patient with Crohn's disease.
作者信息
Ishimoto Hiroshi, Isomoto Hajime, Shikuwa Saburo, Wen Chun-Yang, Suematu Takashi, Ito Masahiro, Murata Ikuo, Ishibashi Hiromi, Kohno Shigeru
机构信息
Department of Internal Medicine, National Nagasaki Medical Center, 2-1001 Kubara, Omura, Nagasaki 856-8562, Japan.
出版信息
World J Gastroenterol. 2004 Sep 15;10(18):2767-8. doi: 10.3748/wjg.v10.i18.2767.
We presented a 20-year-old patient with Crohn's disease (CD). Colonoscopy revealed longitudinal ulceration in the terminal ileum and rectal aphtoid ulcers. After treatment with mesalamine and total parenteral nutrition, repeat colonoscopy revealed a granular elevated area in the terminal ileum, which appeared as an irregular dome-like elevation with irregularly arranged villi on magnifying endoscopy. Biopsy specimens taken from the region showed microgranulomas and lymphoid hyperplasia. Scanning electron microscopy revealed the presence of M cells, confirming that the area corresponded to Peyer's patches. Peyer's patches by magnifying endoscopy and electron microscopy may provide insights into the pathogenesis of CD.
我们报告了一名20岁的克罗恩病（CD）患者。结肠镜检查显示回肠末端有纵行溃疡以及直肠阿弗他溃疡。在接受美沙拉嗪和全胃肠外营养治疗后，复查结肠镜发现回肠末端有一个颗粒状隆起区域，在放大内镜下表现为不规则的圆顶状隆起，绒毛排列不规则。从该区域获取的活检标本显示有微肉芽肿和淋巴组织增生。扫描电子显微镜检查发现存在M细胞，证实该区域对应于派尔集合淋巴结。通过放大内镜和电子显微镜观察派尔集合淋巴结可能有助于深入了解CD的发病机制。
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